PREMPRO
Used for Menopause
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Manufactured by Pfizer
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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PREMPRO Uses, Side Effects, Interactions, Warnings & Dosing
What is PREMPRO?
PREMPRO is the brand name for conjugated estrogens/medroxyprogesterone acetate and is available as an oral tablet.
What dosages is PREMPRO available in?
PREMPRO is available as an oral tablet that contains 0.3 mg CE plus 1.5 mg MPA, 0.45 mg CE plus 1.5 mg MPA, 0.625 mg CE plus 2.5 mg MPA, or 0.625 mg CE plus 5 mg MPA.
What is PREMPRO used for?
PREMPRO is an estrogen replacement / progestin and is used for the following:
- Hot flashes, night sweats, and flushes caused by menopause
- Vaginal dryness and burning caused by menopause
- Prevention of postmenopausal osteoporosis (not a first-choice)
How does PREMPRO work?
PREMPRO is a combination of two medications. Conjugated estrogens is a mixture of estrogens that replaces the estrogen your body loses during menopause. It relieves hot flashes, relieves vaginal dryness, and strengthens bones. Medroxyprogesterone is a progestin that protects the uterus from damage and helps prevent uterine cancer.
How do I take PREMPRO?
PREMPRO: Take 1 tablet by mouth once daily. Since there are many strengths of conjugated estrogens and medroxyprogesterone available, ask your provider which combination strength you should be taking.
Is it safe for me to take PREMPRO?
PREMPRO is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if any of the following apply:
- Undiagnosed abnormal genital bleeding
- Known, suspected, or history of breast cancer
- Known or suspected estrogen-dependent neoplasia
- Active DVT, PE, or a history of these conditions
- Active arterial thromboembolic disease (for example, stroke and MI), or a history of these conditions
- Known anaphylactic reaction oar ngioedema to PREMPRO/PREMPHASE
- Known liver dysfunction or disease
- Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders.
- Known or suspected pregnancy
PREMPRO Common Side Effects
Common side effects of PREMPRO:
- Breast pain
- Headaches
- Stomach pain
- Menstrual cramps
- Gas
- Nausea
- Depression
- More vaginal discharge than usual
PREMPRO Serious Side Effects
Serious side effects are rare with PREMPRO. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions
- Heart attack: chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
- Stroke: sudden trouble talking, trouble walking, or numbness on one side of your body or face
- Shortness of breath
- Sudden, severe headaches
- Breast lumps or pain
- Unusual or heavy vaginal bleeding
Effects of other drugs, drug classes and over-the-counter products on PREMPRO
The following medications may interact with PREMPRO:
- Inducers and/or inhibitors of CYP3A4 may affect estrogen drug metabolism
- Aminoglutethimide administered concomitantly with MPA may significantly depress the bioavailability of medroxyprogesterone acetate
Who makes PREMPRO?
Pfizer
Is PREMPRO safe in pregnancy?
PREMPRO and PREMPHASE should not be used during pregnancy
What to do if you missed your PREMPRO dose
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
What is Prempro used for?
How long should a woman take Prempro for?
Will HRT help me lose belly fat?
How long can you stay on Prempro?
What to expect when starting Prempro?
Does Prempro help with hair loss?
What kind of estrogen is in Prempro?
Does insurance cover Prempro?
Do you gain weight on Prempro?
Can HRT reduce belly fat?
Will estrogen help me lose weight?
What are the best weight loss pills for menopause?
What hormones help you lose weight?
Should I take Prempro in the morning or night?
Does HRT cause belly fat?
Why was Prempro taken off the market?
How long should you stay on Prempro?
What are the side effects of taking Prempro?
Can Prempro be stopped abruptly?
What is the closest generic to Prempro?
How long does it take for Prempro to stop hot flashes?
Is Prempro considered HRT?
How long does it take Prempro to start working?
Will HRT help me lose weight?
Do you lose weight when you stop HRT?
Does HRT cause weight gain?
What is the difference between Prempro and estradiol?
What happens when you stop taking Prempro?
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