How can I lower the cost of my PREMPHASE

You can lower cost of your PREMPHASE using one of the 4 following drug savings programs: Rx Advantage Card for PREMPHASE, Canadian Prescription Savings for PREMPHASE, PREMPHASE Drug Coupons, PREMPHASE Patient Assistance Programs

PREMPHASE Coupon, Savings Card and Patient Assistance

Home

Medications

PREMPHASE

Used for Menopause

Are you tired of high medication costs? Our service offers unbeatable savings on your PREMPHASE prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by Pfizer

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

Start Saving Today!

Lower the cost of your PREMPHASE prescription

You can lower cost of your PREMPHASE using one of the 4 following drug savings programs

Qualified
Rx Advantage Card
Save up to 90%

Check now
Unavailable
Options*
Medication not available
N/A
Manufactured by
N/A
Powered by
Canadian Prescription Savings
Unavailable
Unavailable
Drug Coupons
Unavailable
Available
Patient Assistance Programs
You can receive for FREE

Check now

scrollable

PREMPHASE Uses, Side Effects, Interactions, Warnings & Dosing

Medically reviewed by Jamie Winn, Pharm.D

Written by Rajive Patel, B.Pharm

What is PREMPHASE?

PREMPHASE is the brand name for conjugated estrogens/medroxyprogesterone acetate and is available as an oral tablet.

What dosages is PREMPHASE available in?

PREMPHASE is available as an oral tablet that contains 0.625 mg CE and 0.625 mg CE plus 5 mg MPA.

What is PREMPHASE used for?

PREMPHASE is an estrogen replacement / progestin and is used for the following:

Hot flashes, night sweats, and flushes caused by menopause
Vaginal dryness and burning caused by menopause
Prevention of postmenopausal osteoporosis (not a first-choice)

How does PREMPHASE work?

PREMPHASE is a combination of two medications. Conjugated estrogens is a mixture of estrogens that replaces the estrogen your body loses during menopause. It relieves hot flashes, relieves vaginal dryness, and strengthens bones. Medroxyprogesterone is a progestin that protects the uterus from damage and helps prevent uterine cancer.

How do I take PREMPHASE?

PREMPHASE: There are 2 different colored tablets in the package. Take 1 dark red tablet by mouth once daily on days 1 through 14. Take 1 light blue tablet by mouth once daily on days 15 through 28. The dark-red tablet contains 0.625 mg of conjugated estrogens only, and the light blue tablet contains 0.625 mg conjugated estrogens and 5 mg of medroxyprogesterone.

Is it safe for me to take PREMPHASE?

PREMPHASE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if any of the following apply:

Undiagnosed abnormal genital bleeding
Known, suspected, or history of breast cancer
Known or suspected estrogen-dependent neoplasia
Active DVT, PE, or a history of these conditions
Active arterial thromboembolic disease (for example, stroke and MI), or a history of these conditions
Known anaphylactic reaction or angioedema to PREMPRO/PREMPHASE
Known liver dysfunction or disease
Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders
Known or suspected pregnancy

PREMPHASE Common Side Effects

Common side effects of PREMPHASE:

Breast pain
Headaches
Stomach pain
Menstrual cramps
Gas
Nausea
Depression
More vaginal discharge than usual

PREMPHASE Serious Side Effects

Serious side effects are rare with PREMPHASE. Contact your healthcare provider immediately if you experience any of the following.

Allergic reactions
Heart attack: chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
Stroke: sudden trouble talking, trouble walking, or numbness on one side of your body or face
Shortness of breath
Sudden, severe headaches
Breast lumps or pain
Unusual or heavy vaginal bleeding

Effects of other drugs, drug classes and over-the-counter products on PREMPHASE

The following medications may interact with PREMPHASE:

Inducers and/or inhibitors of CYP3A4 may affect estrogen drug metabolism
Aminoglutethimide administered concomitantly with MPA may significantly depress the bioavailability of medroxyprogesterone acetate

Who makes PREMPHASE?

Pfizer

Is PREMPHASE safe in pregnancy?

PREMPRO and PREMPHASE should not be used during pregnancy.

What is the generic name for PREMPHASE?

conjugated estrogens plus medroxyprogesterone acetate

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects

Drug Savings Tips

How can NowPatient help me to lower the cost of my PREMPHASE prescription?

How do the NowPatient PREMPHASE savings programs work?

Are the NowPatient PREMPHASE savings programs suitable for everyone, regardless of insurance status?

	Rx Advantage Card* for PREMPHASE	Canadian Prescription Savings* for PREMPHASE	PREMPHASE Drug Coupon*	PREMPHASE Patient Assistance Program*
Insured (federal, state or government)	Available	Available	Not Available	Available If Offered by Pharmaceutical Company
Insured (Commercial or Private)	Available	Available	Available If Offered by Pharmaceutical Company	Available If Offered by Pharmaceutical Company
Uninsured	Available	Available	Not Available	Available If Offered by Pharmaceutical Company
Insured but without pharmacy benefit or drug coverage	Available	Available	Not Available	Available If Offered by Pharmaceutical Company

Are the NowPatient drug savings programs suitable for brand and generic versions of PREMPHASE?

	Rx Advantage Card* for PREMPHASE	Canadian Prescription Savings* for PREMPHASE	PREMPHASE Drug Coupon*	PREMPHASE Patient Assistance Program*
Brand	Yes	Yes	Yes, If Offered by Pharmaceutical Company	Yes, If Offered by Pharmaceutical Company
Generic	Yes	Yes	No	No

If you have Medicare Part D or Medicare Advantage and none of the PREMPHASE savings options are applicable or affordable for me, what can you do?

I am uninsured or underinsured and none of the PREMPHASE prescription saving options are applicable or affordable for me, what can I do?

I am commercially or privately insured and none of the PREMPHASE prescription saving options are applicable or affordable for me, what can I do?

If I have federal, state or commercial insurance and none of the PREMPHASE prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?

If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:

1. Patient Access Network Foundation (PAN) assistance for PREMPHASE

If you are having trouble paying for your PREMPHASE medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for PREMPHASE you will need to meet one or all of the following criteria:

Your income is below 400% of the federal poverty level
PREMPHASE is prescribed for an approved FDA indication
You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
You have Medicare insurance coverage that covers PREMPHASE
If PREMPHASE is listed on PAN’s list of covered medications

You can check the Patient Access Network Foundation Website for more information.

2. HealthWell Foundation Copay Program for PREMPHASE

If you are having trouble paying for your PREMPHASE medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for PREMPHASE you will need to meet the following criteria:

You live in and are being treated in the United States
You are insured and your plan covers PREMPHASE
If PREMPHASE is listed on the HealthWell Foundation’s list of covered medications

You can check the HealthWell Foundation Website for more information.

3. Patient Advocate Foundation Co-Pay Relief Program for PREMPHASE

Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your PREMPHASE treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for PREMPHASE you will need to meet the following criteria:

You must be currently insured and have coverage for PREMPHASE
You must have a confirmed diagnosis and treatment plan
You must reside and receive treatment in the United States
Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.

You can check the Patient Advocate Foundation Website for more information.

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Data Security

Our Commitment to You.

Find out more

WHY WE BUILT NOWPATIENT

To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.