PREMARIN VAGINAL CREAM
Used for Menopause
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Manufactured by Pfizer
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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PREMARIN VAGINAL CREAM Uses, Side Effects, Interactions, Warnings & Dosing
What is PREMARIN VAGINAL CREAM?
PREMARIN VAGINAL CREAM is the brand name for conjugated estrogens and is available as a vaginal cream.
What dosages is PREMARIN VAGINAL CREAM available in?
PREMARIN VAGINAL CREAM is available as a vaginal cream that contains 0.625 mg/g.
What is PREMARIN VAGINAL CREAM used for?
PREMARIN VAGINAL CREAM is an estrogen replacement and is used for the following:
- Vaginal thinning, dryness, and pain
- Severe itching and inflammation in the vagina
- Pain during vaginal sex caused by menopause
How does PREMARIN VAGINAL CREAM work?
PREMARIN VAGINAL CREAM contains a type of estrogen, a natural hormone in your body. This medication replaces the estrogen that your body loses during menopause. Replacing estrogen strengthens bones and relieves symptoms of menopause, like vaginal dryness and irritation, hot flashes, and night sweats. The vaginal cream only works in the vagina where you apply it, so it only relieves vaginal dryness and irritation.
How do I take PREMARIN VAGINAL CREAM?
PREMARIN VAGINAL CREAM is dosed as follows:
Vaginal thinning caused by conditions other than menopause: Using the included applicator, apply 0.5 grams to into the vagina once a day for 3 weeks, then apply no cream for 1 week. Then this cycle is repeated. Vaginal dryness and irritation casued by menopause: Using the included applicator, apply 0.5 grams into the vagina twice a week.
Is it safe for me to take PREMARIN VAGINAL CREAM?
PREMARIN VAGINAL CREAM is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if the following apply:
- Undiagnosed abnormal genital bleeding
- Known, suspected, or history of breast cancer except in appropriately selected patients being treated for metastatic diseases.
- Known or suspected estrogen-dependent neoplasia
- Active DVT, PE, or a history of these conditions. Active arterial thromboembolic disease (for example, stroke and MI), or a history of these conditions.
- Known anaphylactic reaction or angioedema with PREMARIN
- Known liver impairment or disease
- Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders
- Known or suspected pregnancy
PREMARIN VAGINAL CREAM Common Side Effects
Common side effects of PREMARIN VAGINAL CREAM:
- Breast pain
- Headache
- Pelvic pain
- Vaginal discharge
PREMARIN VAGINAL CREAM Serious Side Effects
Serious side effects are rare with PREMARIN VAGINAL CREAM. Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: rash, itching, swollen lips or tongue, trouble breathing, stomach pain, vomiting
- Heart attack: chest pain or tightness, shortness or breath, sweating, nausea, pain that radiates up to your shoulder, arm, neck, or jaw
- Stroke: sudden trouble talking or walking, numbness on one side of your body or face, severe headache, dizziness, confusion
- Blood clot: chest pain, shortness of breath, dizziness, fast heart rate, swelling, pain, or redness in the arms or legs
- Cancer: lumps, pain, swelling, or changes in the breasts; swollen lymph nodes, unusual or heavy vaginal bleeding, bloating, extreme tiredness, stomach-area pain
Effects of other drugs, drug classes and over-the-counter products on PREMARIN VAGINAL CREAM
The following medications may interact with PREMARIN VAGINAL CREAM:
- Inducers and/or inhibitors of CYP3A4 may affect estrogen drug metabolism
Who makes PREMARIN VAGINAL CREAM?
Pfizer
Is PREMARIN VAGINAL CREAM safe in pregnancy?
PREMARIN VAGINAL CREAM should not be used during pregnancy.
What is the generic name for PREMARIN VAGINAL CREAM?
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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