olmesartan/amlodipine
Used for Hypertension
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Manufactured by various FDA-approved generic manufacturers.
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olmesartan/amlodipine Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is olmesartan/amlodipine available in?
olmesartan/amlodipine is available as a combination of olmesartan, amlodipine, and hydrochlorothiazide and is available in strengths of: 20 mg/5 mg/12.5 mg, 40 mg/5 mg/12.5 mg, 40 mg/5 mg/25 mg, 40 mg/10 mg/12.5 mg, and 40 mg/10 mg/25 mg.
What is olmesartan/amlodipine used for?
olmesartan/amlodipine is an ARB / CCB / Diuretic (water pill) and is used to treat high blood pressure.
How does olmesartan/amlodipine work?
olmesartan/amlodipine is a combination of three medications that lower blood pressure. Olmesartan is an angiotensin II receptor blocker (ARB). Angiotensin II is a hormone that normally attaches to its signaling proteins (receptors) in the body to raise your blood pressure. Olmesartan blocks this interaction from happening to lower your blood pressure. Amlodipine is a calcium channel blocker (CCB). It works by relaxing your blood vessels to lower your blood pressure. Hydrochlorothiazide is a thiazide diuretic (water pill). It works in your kidneys to remove extra water and certain electrolytes, like sodium and potassium. This helps lower blood pressure.
How do I take olmesartan/amlodipine?
The typical starting dose for olmesartan/amlodipine is 20 mg/5 mg/12.5 mg (olmesartan/amlodipine/hydrochlorothiazide) by mouth once daily. Your provider will adjust your dose based on how well it’s helping your blood pressure and if you’re having side effects. The maximum dose is 40 mg/10 mg/25 mg (olmesartan/amlodipine/hydrochlorothiazide) once daily.
Is it safe for me to take olmesartan/amlodipine?
olmesartan/amlodipine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have
olmesartan/amlodipine Common Side Effects
Common side effects of olmesartan/amlodipine:
- Dizziness
- Swelling of legs or arms
- Headache
- Tiredness
- Runny nose, sore throat, and other cold-like symptoms
olmesartan/amlodipine Serious Side Effects
Serious side effects are rare with olmesartan/amlodipine. Contact your healthcare provider immediately if you experience any of the following.
- Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint or fainting
- Heart attack: tightness and pain in the chest, neck, arms, or back; cold and clammy skin; sweating; dizziness; tiredness
- Kidney problems: urinating less often than usual; swelling in your feet, ankles, or hands; unexplained weight gain
- High blood potassium levels: nausea, muscle weakness, abnormal heartbeat
- Severe diarrhea
Effects of other drugs, drug classes and over-the-counter products on olmesartan/amlodipine
The following medications may interact with olmesartan/amlodipine:
Olmesartan medoxomil:
- Nonsteroidal anti-inflammatory drugs (NSAIDS): May lead to increased risk of renal impairment and loss of antihypertensive effect.
- Dual inhibition of the renin-angiotensin system: Increased risk of renal impairment, hypotension, and hyperkalemia.
Amlodipine:
- If simvastatin is co-administered with amlodipine, do not exceed doses
- greater than 20 mg daily of simvastatin.
Hydrochlorothiazide:
- Alcohol, barbiturates, narcotics: Potentiation of orthostatic hypotension
- Antidiabetic drugs: Dosage adjustment of antidiabetic may be required
- Cholestyramine and colestipol: Reduced absorption of thiazides
- Corticosteroids, ACTH: Electrolyte depletion, hypokalemia
- Lithium: Reduced renal clearance and high risk of lithium toxicity when used with diuretics. Should not be given with diuretics
- NSAIDs: Can reduce the diuretic, natriuretic, and antihypertensive effects of diuretics
Who makes olmesartan/amlodipine?
Various FDA-approved generic manufacturers
Is olmesartan/amlodipine safe in pregnancy?
olmesartan/amlodipine can cause harm or death to an unborn baby.
Talk to your doctor about other ways to lower your blood pressure if you plan to become pregnant. If you get pregnant while taking olmesartan/amlodipine, tell your doctor right away.
What to do if you missed your olmesartan/amlodipine dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Related Conditions
Things to know
What is olmesartan and amlodipine used for?
What are 4 worst blood pressure drugs?
Does olmesartan cause weight gain?
What should you avoid when taking amlodipine?
Does amlodipine cause weight gain?
Should I take amlodipine and olmesartan together?
How long does amlodipine and olmesartan take to work?
How long does it take for amlodipine olmesartan to work?
When is the best time to take olmesartan blood pressure medication?
Does amlodipine olmesartan have a diuretic?
When is the best time to take amlodipine olmesartan?
Can you eat bananas while taking amlodipine?
Does olmesartan lower blood pressure quickly?
What is the biggest side effect of amlodipine?
Can I drink coffee while taking amlodipine?
Does amlodipine make you pee at night?
Should I take olmesartan in AM or PM?
Is it better to take amlodipine in morning or evening?
Is 5mg amlodipine enough to lower blood pressure?
How many hours does it take for amlodipine to lower blood pressure?
What are the most common side effects of olmesartan?
What is the controversy with olmesartan?
Is weight gain a side effect of olmesartan?
Is olmesartan bad for kidneys?
What are the 4 best blood pressure drugs?
What is the safest blood pressure medicine?
What are the top 3 side effects of amlodipine?
Is olmesartan a good blood pressure medication?
Why was olmesartan discontinued?
Should I take olmesartan in the morning or night?
Who should not take olmesartan?
What fruits interfere with high blood pressure medication?
Is olmesartan good for the heart?
What to avoid when taking olmesartan?
What is the best time of day to take olmesartan?
What foods should you avoid while taking amlodipine?
Does olmesartan interfere with sleep?
What food interacts with olmesartan?
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