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Azor is the brand name for amlodipine and olmesartan medoxomil oral tablets.

Azor is available as an oral tablet that contains a combination of amlodipine/olmesartan medoxomil in strengths of:

• 5 mg/20 mg
• 10 mg/20 mg
• 5 mg/40 mg
• 10 mg/40 mg

Azor is a CCB / ARB and is used to treat high blood pressure.

Azor is a combination of two medications that work together to lower blood pressure. Amlodipine is a calcium channel blocker (CCB). It works by relaxing your blood vessels to lower your blood pressure. Olmesartan is an angiotensin II receptor blocker (ARB). Angiotensin II is a hormone that normally attaches to its signaling proteins (receptors) in the body to raise your blood pressure. Olmesartan blocks this interaction from happening to lower your blood pressure.

The typical starting dose is 5 mg/20 mg (amlodipine/olmesartan) by mouth once per day. Your provider will adjust your dose based on how well it’s helping your blood pressure and if you’re having side effects. The maximum dose is 10 mg/40 mg (amlodipine/olmesartan) once per day.

Azor is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have diabetes.

Common side effects of Azor:

• Swelling
• Dizziness
• Headache

Serious side effects are rare with Azor. Contact your healthcare provider immediately if you experience any of the following.

• Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint or fainting
• Heart attack: tightness and pain in the chest, neck, arms, or back; cold and clammy skin; sweating; dizziness; tiredness
• Kidney problems: urinating less often than usual; swelling in your feet, ankles, or hands; unexplained weight gain
• High blood potassium levels: nausea, muscle weakness, tingling sensation, abnormal heartbeat
• Severe, long-term diarrhea with weight loss

The following medications may interact with Azor:

Amlodipine:

• If simvastatin is co-administered with amlodipine, do not exceed doses greater than 20 mg daily of simvastatin
• Increased exposure of cyclosporin and tacrolimus
• Increased exposure of amlodipine when coadminstred with CYP3A inhibitors

Olmesartan medoxomil:

• Nonsteroidal anti-inflammatory drugs (NSAIDS) may lead to increased risk of renal impairment and loss of antihypertensive effect
• Dual inhibition of the renin-angiotensin system:
• Increased risk of renal impairment, hypotension, and hyperkalemia
• Colesevelam hydrochloride: Consider administering olmesartan at least
• 4 hours before colesevelam hydrochloride dose
• Lithium: Increases in serum lithium concentrations and lithium toxicity

Daiichi Sankyo, Inc.

Azor can cause harm or death to an unborn baby.
Talk to your doctor about other ways to lower your blood pressure if you plan to become pregnant.
If you get pregnant while taking Azor, tell your doctor right away.

• Olmesartan/Amlodipine