Norgestimate Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Norgestimate / Ethinyl Estradiol
    Generic for Tri-Cyclen
    0.18/35-0.215/35-0.25/35 mg/mcg
    28 blister pack of tabletss $7.03 USD
    Save $21.84
  3. Norgestimate & Ethinyl Estradiol
    Generic for Tri-Lo-Sprintec
    0.18/25-0.215/25-0.25/25 mg/mcg
    28 blister pack of tabletss $5.36 USD
    Save $49.16
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Do you need a prescription for norgestimate?

Yes, norgestimate is only available with a valid physician Rx.

How much is norgestimate without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase norgestimate, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for norgestimate in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a norgestimate savings card?

Yes. Save up to 90% on your norgestimate with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a norgestimate coupon provider in the US?

No. Now Patient does not provide norgestimate coupons or FREE norgestimate samples.

Do you accept commercial, Medicare or Medicaid coverage for norgestimate in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much norgestimate?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using norgestimate. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much norgestimate. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic norgestimate?

Generic norgestimate refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of norgestimate

Norgestimate is approved by the U.S. Food and Drug Administration (FDA) for use in combination with ethinyl estradiol as an oral contraceptive.

Active ingredient of norgestimate

The active ingredient of norgestimate is norgestimate.

US brand name of norgestimate and manufacturer

Norgestimate is available in the US under various brand names, including Estarylla, Mono-linyah, MonoNessa, (norgestimate/ethinyl estradiol), Ortho Tri-Cyclen-Lo, Tri-Previfem, Tri-estarylla, Tri-linyah, Tri-mili, Tri-previfem, Tri-lo-sprintec, and Trinessa. It is manufactured by different pharmaceutical companies.

UK brand name of norgestimate and manufacturer

In the UK, norgestimate is available under various brand names, including Cilest, Lizinna, and Rigevidon. The manufacturer may vary depending on the brand name.

Prescription requirement for norgestimate

A prescription (Rx) is required for norgestimate in both the US and the UK.

Availability of norgestimate in the UK with NHS prescription

Norgestimate is available in the UK with an NHS prescription.

Conditions treated by norgestimate

Norgestimate is primarily used as an oral hormonal contraceptive to prevent pregnancy. It may be used in combination with estrogen. Birth control pills may also help to make your periods more regular. This medication does not protect you from sexually transmitted diseases.

How does norgestimate work?

Norgestimate, in combination with ethinyl estradiol, works by preventing ovulation (the release of an egg from the ovary), thickening the cervical mucus to inhibit sperm penetration, and altering the uterine lining to make it less receptive to implantation.

Forms of norgestimate available

Norgestimate is available in the form of oral tablets.

Dosage of norgestimate

The dosage of norgestimate may vary depending on the specific brand and formulation. It is important to follow the recommended dosage instructions provided by a healthcare professional.

Directions for norgestimate use

Norgestimate should be taken exactly as directed by the healthcare provider. The medication is usually taken orally once daily, with or without food. It is important to take norgestimate consistently and continue the prescribed treatment course.

Warnings and precautions for norgestimate

  • Norgestimate is contraindicated in certain conditions, such as pregnancy, breastfeeding, and a history of blood clots or certain cancers. It may also have interactions with certain medications. It is important to discuss all medical conditions and medications with the healthcare provider before starting norgestimate
  • Do not take norgestimate if you smoke and are over 35 years of age, have ever had blood clots in your arms, legs, or lungs, have had a heart attack, stroke, high blood pressure, severe migraine headaches, liver disease, including liver tumors, unexplained vaginal bleeding or breast cancer

Use of norgestimate during pregnancy

Norgestimate is not intended for use during pregnancy. It is important to discontinue norgestimate and use alternative methods of contraception if pregnancy is suspected or confirmed.

Use of norgestimate while breastfeeding

Norgestimate is not recommended for use while breastfeeding. Alternative forms of contraception should be considered.

Possible side effects of norgestimate

Common side effects of norgestimate may include headache, breast tenderness, nausea, stomach pain, and breakthrough bleeding. Serious side effects are rare but may include allergic reactions (shortness of breath, chest pain, trouble breathing, hives), blood clots, high blood pressure, severe headaches, and liver problems (dark urine, yellowing of the eyes and skin). Promptly report any concerning symptoms to a healthcare provider.

Interactions with other drugs

Norgestimate may interact with other medications, including aromatase inhibitors (such as anastrozole), rifamycins (such as rifabutin), griseofulvin, treatments for Hepatitis C (such as ombitasvir/paritaprevir/ritonavir, with or without dasabuvir), and St. John’s wort.

It is important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, supplements, and herbal products, to avoid any adverse events and potential drug interactions.

Similar drugs to norgestimate

Other combination oral contraceptives that contain norgestimate or similar progestins, combined with ethinyl estradiol, are available under various brand names.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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