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MEDICAL INFORMATION
Macrodantin Key Facts
What is Macrodantin?
Macrodantin is the brand name for nitrofurantoin and is available as an oral capsule.
What dosages is Macrodantin available in?
Macrodantin is available as a 25 mg, 50 mg, and 100 mg oral capsule.
What is Macrodantin used for?
Macrodantin is a nitrofuran antibiotic that is used to treat urinary tract infections.
How does Macrodantin work?
Macrodantin is a nitrofuran antibiotic. The medication collects in your urine. It kills bacteria in the urinary tract by damaging or blocking proteins the bacteria need to survive.
How do I take Macrodantin?
For adults, the typical dose is 50 mg to 100 mg by mouth four times a day with food. For children ages 1 month and older, the dose will depend on their body weight.
Is it safe for me to take Macrodantin?
Macrodantin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have anuria, oliguria, or significant impairment of renal function, a previous history of cholestatic jaundice/hepatic dysfunction associated with nitrofurantoin, or pregnant at term (38-42 weeks gestation).
Macrodantin Common Side Effects
Common side effects of Macrodantin:
- Nausea
- Headache
- Gas
- Diarrhea
- Vomiting
- Upset stomach
- Stomach pain
Macrodantin Serious Side Effects
Serious side effects are rare with Macrodantin. Serious Side Effects Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: hives, rash, muscle aches, chills, fever, swelling of the lips or tongue, difficulty breathing
- Severe diarrhea
- Trouble breathing or new or worsening cough
- Liver problems: stomach bloating, severe stomach pain with vomiting, yellowing of your skin or the whites of your eyes, dark urine
Effects of other drugs, drug classes and over-the-counter products on Macrodantin
The following medications may interact with Macrodantin:
- Antacids containing magnesium trisilicate, when administered concomitantly with nitrofurantoin, reduce both the rate and extent of absorption
- Uricosuric drugs, such as probenecid and sulfinpyrazone, can inhibit renal tubular secretion of nitrofurantoin. The resulting increase in nitrofurantoin serum levels may increase toxicity, and the decreased urinary levels could lessen its efficacy as a urinary tract antibacterial
Who makes Macrodantin?
Procter & Gamble Pharmaceuticals, Inc.
Is Macrodantin safe in pregnancy?
Macrodantin is contraindicated in pregnant patients at term (38-42 weeks gestation), during labor and delivery, or when the onset of labor is imminent. It is contraindicated in neonates under one month of age.
What is the generic name for Macrodantin?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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