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MEDICAL INFORMATION
Fezolinetant Key Facts
What dosages is Fezolinetant available in?
Fezolinetant is available as a 45 mg oral tablet.
What is Fezolinetant used for?
Fezolinetant is a neurokinin 3 (NK3) receptor antagonist that is used to treat moderate-to-severe hot flashes and night sweats due to menopause.
How does Fezolinetant work?
Fezolinetant blocks a chemical in the brain called neurokinin B from causing hot flashes (episodes of sweating and feeling hot).
How do I take Fezolinetant?
Fezolinetant is typically taken as 45 mg by mouth once daily.
Is it safe for me to take Fezolinetant?
Fezolinetant is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Known cirrhosis
- Severe renal impairment or end-stage renal disease
- Concomitant use with CYP1A2 inhibitors
Fezolinetant Common Side Effects
Common side effects of Fezolinetant:
- Stomach pain
- Diarrhea
- Trouble sleeping
- Back pain
- Hot flush
- Higher liver labs, suggesting liver irritation
Fezolinetant Serious Side Effects
Serious side effects are rare with Fezolinetant. Contact your healthcare provider immediately if you experience any of the following.
- Serious liver damage: nausea, vomiting, stomach pain, yellowing of the skin or whites of the eyes, clay-colored stools
Effects of other drugs, drug classes and over-the-counter products on Fezolinetant
The following medications may interact with Fezolinetant:
- Fezolinetant is contraindicated in individuals using CYP1A2 inhibitors
Who makes Fezolinetant?
Various FDA-approved generic manufacturers
Is Fezolinetant safe in pregnancy?
It is not known if Fezolinetant will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.
What is the brand name for Fezolinetant?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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