Used for Menopause

Are you tired of high medication costs? Our service offers unbeatable savings on your CLIMARA prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by Bayer HealthCare Pharmaceuticals Inc.

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

CLIMARA cost saving options available to you

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    Rx Advantage Card

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    You can save up to 90%

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    Canadian Prescription Savings

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    Buy your CLIMARA without insurance from Canada at discounts of up to 90% using NowPatient's Canadian Prescription savings program.
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    Drug Coupons

    Obtain your CLIMARA for as little as $0 per fill. Suitable for insured individuals only.
  • Unavailable

    Patient Assistance Programs

    Obtain your CLIMARA at no cost. Suitable for insured, underinsured and uninsured individuals

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CLIMARA Uses, Side Effects, Interactions, Warnings & Dosing

What is CLIMARA?

What is CLIMARA?

CLIMARA is the brand name for estradiol and is available as a transdermal patch.

What dosages is CLIMARA available in?

What dosages is CLIMARA available in?

CLIMARA is available as a transdermal patch that delivers 0.025 mg, 0.0375 mg, 0.05 mg, 0.075 mg, and 0.1 mg of estradiol per day.

What is CLIMARA used for?

What is CLIMARA used for?

CLIMARA is an estrogen replacement that is used to prevent bone loss and relieve symptoms of menopause, such as hot flashes and vaginal dryness.

How does CLIMARA work?

How does CLIMARA work?

CLIMARA replaces estrogen hormones that your body loses during menopause to relieve symptoms of menopause and prevent bone loss.

How do I take CLIMARA?

How do I take CLIMARA?

The starting dose of CLIMARA is started low and then increased as needed. It is a patch that is placed on the lower part of the stomach or upper part of the buttocks and replaced weekly.

Is it safe for me to take CLIMARA?

Is it safe for me to take CLIMARA?

CLIMARA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take CLIMARA if you are a woman who is over 35 years old and smoke. It should also not be used in women with any of the following medical conditions:

  • Undiagnosed abnormal vaginal bleeding
  • Known, suspected, or history of breast cancer
  • Known or suspected estrogen-dependent cancer
  • Active or history of deep vein thrombosis or pulmonary embolism
  • Stroke or myocardial infarction (heart attack) within the past year
  • Liver disease
  • Allergy to any of the ingredients in Activella
  • Known or suspected pregnancy
CLIMARA Common Side Effects

CLIMARA Common Side Effects

Common side effects of CLIMARA include:

  • Headache
  • Breast pain or tenderness
  • Flu-like symptoms
  • Stomach pain
  • Swelling
  • Back and body pain
  • Depression
  • Vaginal spotting
  • Upset stomach
  • Weight gain
  • Rashes
  • Vaginal discharge
  • Itching
  • Nausea
CLIMARA Serious Side Effects

CLIMARA Serious Side Effects

Serious side effects are rare with CLIMARA. Contact your healthcare provider immediately if you experience any of the following such as allergic reactions; heart attack (hest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw); stroke (sudden trouble talking, trouble walking, numbness on one side of your body or face, sudden, severe headaches); shortness of breath; breast lumps or pain; unusual or heavy vaginal bleeding; gallbladder problems (stomach pain, nausea or vomiting that doesn’t go away, fever, yellowing of the skin and eyes).

Effects of other drugs, drug classes and over-the-counter products on CLIMARA

Effects of other drugs, drug classes and over-the-counter products on CLIMARA

The following medications may interact with CLIMARA:

  • Inducers of CYP3A4 such as St. John’s wort (Hypericum perforatum) preparations, phenobarbital, carbamazepine, and rifampin may reduce the levels and effects of CLIMARA
  • Inhibitors of CYP3A4 such as erythromycin, clarithromycin, ketoconazole, itraconazole, ritonavir and grapefruit juice may increase the levels and effects of CLIMARA
Who makes CLIMARA?

Who makes CLIMARA?

Bayer HealthCare Pharmaceuticals Inc.

Is CLIMARA safe in pregnancy?

Is CLIMARA safe in pregnancy?

CLIMARA should not be used during pregnancy.


What to do if you missed your CLIMARA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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