Used for Cancer

View ZYTIGA savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or ZYTIGA Patient Assistance Program.

Programs are suitable for individuals who want to buy ZYTIGA without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Janssen Pharmaceuticals

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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    Rx Advantage Card

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    Save up to 90%

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    Drug Coupons

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    Pay as little as $0

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    Patient Assistance Programs

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about ZYTIGA

What is ZYTIGA?

What is ZYTIGA?

ZYTIGA is the brand name for abiraterone and is available as an oral tablet.

What dosages is ZYTIGA available in?

What dosages is ZYTIGA available in?

ZYTIGA is available as 250 mg and 500 mg oral tablet.

What is ZYTIGA used for?

What is ZYTIGA used for?

ZYTIGA is a CYP17 inhibitor indicated in combination with prednisone for the treatment of patients with:

  • metastatic castration-resistant prostate cancer (CRPC)
  • metastatic high-risk castration-sensitive prostate cancer (CSPC)
How does ZYTIGA work?

How does ZYTIGA work?

ZYTIGA works by interrupting the androgen-making process at an important step. It inhibits androgen at 3 sources—the testes, the adrenal glands, AND the tumor itself.

How do I take ZYTIGA?

How do I take ZYTIGA?

ZYTIGA is typically taken for:

Metastatic castration-resistant prostate cancer:

  • ZYTIGA 1,000 mg orally once daily with prednisone 5 mg orally twice daily

Metastatic castration-sensitive prostate cancer:

  • ZYTIGA 1,000 mg orally once daily with prednisone 5 mg orally once daily
  • Patients receiving ZYTIGA should also receive a gonadotropin-releasing
  • hormone (GnRH) analog concurrently or should have had bilateral orchiectomy
  • ZYTIGA tablets must be taken as a single dose once daily on an empty stomach
  • Do not eat food 2 hours before and 1 hour after taking ZYTIGA. The tablets must be swallowed whole with water. Do not crush or chew tablets
Is it safe for me to take ZYTIGA?

Is it safe for me to take ZYTIGA?

ZYTIGA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

ZYTIGA Common Side Effects

ZYTIGA Common Side Effects

Common side effects of ZYTIGA:

  • Fatigue
  • Arthralgia
  • Hypertension
  • Nausea
  • Edema
  • Hypokalemia
  • Hot flush
  • Diarrhea
  • Vomiting
  • Upper respiratory infection
  • Cough
  • Headache
ZYTIGA Serious Side Effects

ZYTIGA Serious Side Effects

Serious side effects are rare with ZYTIGA. Some examples include:

  • High blood pressure (hypertension), low blood potassium levels (hypokalemia), fluid retention (edema), and irregular heartbeats
  • Adrenal problems
  • Severe liver problems
  • Liver problems.
  • Low blood sugar
  • Increased risk of bone fracture and death
Effects of other drugs, drug classes and over-the-counter products on ZYTIGA

Effects of other drugs, drug classes and over-the-counter products on ZYTIGA

The following medications may interact with ZYTIGA:

  • CYP3A4 Inducers: Avoid concomitant strong CYP3A4 inducers during ZYTIGA treatment. If a strong CYP3A4 inducer must be co-administered, increase the ZYTIGA dosing frequency CYP2D6 Substrates: Avoid co-administration of ZYTIGA with CYP2D6 substrates that have a narrow therapeutic index. If an alternative treatment cannot be used, exercise caution and consider a dose reduction of the concomitant CYP2D6 substrate
Who makes ZYTIGA?

Who makes ZYTIGA?

Janssen Pharmaceuticals

Is ZYTIGA safe in pregnancy?

Is ZYTIGA safe in pregnancy?

The safety and efficacy of ZYTIGA have not been established in females. Based on findings from animal studies and the mechanism of action, ZYTIGA can cause fetal harm and potential loss of pregnancy.


What to do if you missed your ZYTIGA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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