Used for Cancer

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Manufactured by Bausch Health

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Updated on 26 Apr 2024

ZYCLARA Uses, Side Effects, Interactions, Warnings & Dosing

What is ZYCLARA?

What is ZYCLARA?

ZYCLARA is the brand name for imiquimod and is available as a topical cream.

What dosages is ZYCLARA available in?

What dosages is ZYCLARA available in?

ZYCLARA is available as a topical cream in strengths of 2.5% and 3.75%.

What is ZYCLARA used for?

What is ZYCLARA used for?

ZYCLARA is a topical skin product and is used for the following:
Face or scalp actinic keratosis (scaly precancerous spot or growth on the skin) in adults – all brands and strengths
Genital and anal warts in adults and children 12 years and older – Zyclara 3.75% and Aldara 5% only Superficial basal cell carcinoma (a type of skin cancer) in adults – Aldara 5% only

How does ZYCLARA work?

How does ZYCLARA work?

ZYCLARA is a topical skin product. It’s not exactly clear how the medication works, but it activates the immune system to fight off certain types of cancer, warts, and skin damage.

How do I take ZYCLARA?

How do I take ZYCLARA?

ZYCLARA is dosed as follows:

Actinic keratosis (adults)

  • ZYCLARA 2.5% and 3.75%: Apply up to 0.5 grams (2 packets or 2 pumps) to the affected area once daily for 2 weeks. Afterwards, stop using the medication for 2 weeks, then use it again
  • Aldara 5%: Apply to the affected area 2 times per week (for example, Monday and Thursday, or Tuesday and Friday) for 16 weeks. Use no more than one packet of Aldara per dose
  • Genital and anal warts in (adults and children 12 years and older)
  • ZYCLARA 3.75%: Apply up to 0.25 grams (1 packet or 1 pump) to the wart once daily until the wart is totally gone, for no more than 8 weeks
  • ldara 5%: Apply to the wart 3 times per week (for example, Monday/Wednesday/Friday or Tuesday/Thursday/Saturday) until the wart is totally gone, for no more than 16 weeks.

Superficial basal cell carcinoma (adults)

  • Aldara 5%: Apply to the affected area 5 times per week (for example, Monday through Friday) for 6 weeks. Your provider will tell you the right amount to use depending on the size of the tumor
Is it safe for me to take ZYCLARA?

Is it safe for me to take ZYCLARA?

ZYCLARA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

ZYCLARA Common Side Effects

ZYCLARA Common Side Effects

Common side effects of ZYCLARA:

  • Skin reaction, including itching, burning, bleeding, stinging, and pain
  • Common cold symptoms
  • Sinus inflammation
  • Headache
ZYCLARA Serious Side Effects

ZYCLARA Serious Side Effects

Serious side effects are rare with ZYCLARA. Contact your healthcare provider immediately if you experience any of the following.

  • Severe skin reactions
  • Difficulty urinating due to genital swelling
Effects of other drugs, drug classes and over-the-counter products on ZYCLARA

Effects of other drugs, drug classes and over-the-counter products on ZYCLARA

There are no major drug interactions listed for ZYCLARA. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Who makes ZYCLARA?

Who makes ZYCLARA?

Bausch Health

Is ZYCLARA safe in pregnancy?

Is ZYCLARA safe in pregnancy?

It is not known if ZYCLARA Cream can harm your unborn baby. Talk to your healthcare provider if you are pregnant or plan to become pregnant.


What to do if you missed your ZYCLARA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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