ImiquimodPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Imiquimod
    Generic for Aldara
    0.25g x 30 packet of creams $25.5 USD
    Save $312.00
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Do you need a prescription for imiquimod?

Yes, imiquimod is only available with a valid physician Rx.

How much is imiquimod without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase imiquimod, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for imiquimod in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a imiquimod savings card?

Yes. Save up to 90% on your imiquimod with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a imiquimod coupon provider in the US?

No. Now Patient does not provide imiquimod coupons or FREE imiquimod samples.

Do you accept commercial, Medicare or Medicaid coverage for imiquimod in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much imiquimod?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using imiquimod. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much imiquimod. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic imiquimod?

Generic imiquimod refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of imiquimod

Imiquimod is approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain skin conditions, including actinic keratosis, superficial basal cell carcinoma, and genital warts.

Active ingredient of imiquimod

The active ingredient of imiquimod is imiquimod.

US brand name of imiquimod and manufacturer

Imiquimod is available under various brand names in the US, including Aldara and Zyclara. These medications are manufactured by different pharmaceutical companies.

UK brand name of imiquimod and manufacturer

In the UK, imiquimod is available under various brand names, and the manufacturers may vary.

Prescription requirement for imiquimod

A prescription (Rx) is required for imiquimod in both the US and the UK.

Availability of imiquimod in the UK with NHS prescription

Imiquimod 5 is available in the UK with an NHS prescription.

Conditions treated by imiquimod

Imiquimod is used to treat certain skin conditions, including actinic keratosis (precancerous skin lesions, scaly growths), superficial basal cell carcinoma (a type of skin cancer), perianal warts and genital warts caused by human papillomavirus (HPV). It may also be used for the treatment of acyclovir-resistant herpes simplex in patients with HIV.

Imiquimod’s mechanism of action

Imiquimod belongs to a class of medications called immune response modifiers. It works by stimulating the immune system to produce interferon and other substances that help the body fight against abnormal skin cells or viral infections.

Forms of imiquimod available

Imiquimod is available in the form of topical imiquimod cream or gel.

Dosage of imiquimod

The dosage of imiquimod may vary depending on the specific condition being treated, the severity of the condition, and individual patient factors. It is important to follow the prescribed dosage instructions provided by the healthcare provider.

Directions for imiquimod use

Imiquimod should be used exactly as directed by the healthcare provider. A thin layer of the cream or gel should be applied to the affected area of the skin and gently rubbed in. It is typically applied once daily for several weeks. Do not cover the treated area with bandages.

Warnings and precautions for imiquimod

  • Imiquimod should not be used on open wounds or broken skin
  • It may cause local skin reactions, including redness, swelling, and irritation at the application site
  • Imiquimod may make your skin more sensitive to the sun. Avoid sunlamps and tanning booths and use sunscreen when outdoors
  • It is important to avoid contact with the eyes, nose, mouth, and other mucous membranes

Interactions with other drugs

There are no significant drug interactions associated with imiquimod. However, it is important to inform the healthcare provider about all medications being used, including over-the-counter products and herbal supplements.

Use of imiquimod during pregnancy

Imiquimod topical treatment should be used during pregnancy only if the potential benefits outweigh the potential risks. Consultation with a healthcare professional is necessary to discuss the specific situation.

Use of imiquimod while breastfeeding

It is not known whether imiquimod passes into breast milk. Consultation with a healthcare provider is necessary to weigh the potential risks and benefits when using imiquimod.

Possible side effects of imiquimod

In clinical trials common side effects of imiquimod may include skin reactions at the application site, such as redness, burning, blisters, swelling, crusting, scabbing, itching, and flaking. Serious side effects are rare but can include severe skin reactions, allergic reactions, and flu-like symptoms.

Interactions with different drugs

Imiquimod may interact with other medications. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medications, salt substitutes, herbal products, supplements, and vitamins you are taking to avoid potential adverse effects and drug interactions.

Similar drugs to imiquimod

Other medications used to treat similar skin conditions include podophyllotoxin, fluorouracil, and cryotherapy (freezing therapy).


  • FDA Prescribing Information for Imiquimod
  • MHRA product information for Imiquimod
  • NHS UK
  • Drugs.com
  • WebMD

About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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