Used for Migraines

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Manufactured by AstraZeneca

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

ZOMIG Uses, Side Effects, Interactions, Warnings & Dosing

What is ZOMIG?

What is ZOMIG?

ZOMIG is the brand name for zolmitriptan and is available as an an oral tablet, orally disintegrating tablet, and a nasal spray.

What dosages is ZOMIG available in?

What dosages is ZOMIG available in?

ZOMIG is available as a 2.5 mg and 5 mg orally disintegrating tablet, oral tablet, and nasal spray.

What is ZOMIG used for?

What is ZOMIG used for?

ZOMIG is a triptan and is used to treat migraines.

How does ZOMIG work?

How does ZOMIG work?

ZOMIG is a triptan. It works by attaching to certain serotonin receptors (proteins) in your brain and nervous system. These proteins react to serotonin, which is a natural chemical in your body that might play a role in migraines. When ZOMIG attaches to these receptors, it’s thought to help lower blood vessel swelling in the brain. It’s also thought to help stop the release of pain signals through your nerves. This helps relieve migraine pain.

How do I take ZOMIG?

How do I take ZOMIG?

ZOMIG is typically taken as a single dose at the first sign of a migraine. If the headache doesn’t go away or it comes back, you can consider taking another dose 2 hours after your previous dose. The maximum single dose is 5 mg. Don’t take more than 10 mg in a 24-hour period.

Is it safe for me to take ZOMIG?

Is it safe for me to take ZOMIG?

ZOMIG is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if any of the following apply to you:

  • History of heart disease (including chest pain or heart attack)
  • Conditions that cause spasms in the heart blood vessels
  • Conditions that cause an irregular heart rhythm (arrhythmias)
  • History of stroke or “mini-stroke”
  • History of migraines with double vision, dizziness, and movement problems or migraines with weakness on one side of the body
  • Conditions affecting the blood vessels or blood supply to your body (like peripheral artery disease or ischemic bowel disease)
  • Uncontrolled high blood pressure
  • Have taken another triptan, ergotamine-containing medication, or ergot-type medication within the past 24 hours
  • Take monoamine oxidase (MAO)-A inhibitors (e.g., phenelzine (Nardil), tranylcypromine (Parnate)) currently or within the past 2 weeks
ZOMIG Common Side Effects

ZOMIG Common Side Effects

Common side effects of ZOMIG:

  • Nausea
  • Dizziness
  • Pins and needles feeling in the arms or legs
  • Neck, throat, or jaw pain, tightness, or pressure
  • Sleepiness
  • Feeling warm or cold
  • Body weakness
  • Dry mouth
  • Chest pain, tightness, pressure, or heaviness
ZOMIG Serious Side Effects

ZOMIG Serious Side Effects

Serious side effects are rare with ZOMIG. Contact your healthcare provider immediately if you experience any of the following.

  • Heart attack: chest or arm pain, shortness of breath, cold sweat
  • Stroke: sudden weakness on one side of your body, headache, changes in your speech or vision, confusion
  • Serotonin syndrome: high fever, racing heart, hallucinations, sudden changes in thought or mood, movement problems
  • Allergic reaction: rash; hives; difficulty breathing or swallowing; swollen face, lips, mouth, tongue, or throat
Effects of other drugs, drug classes and over-the-counter products on ZOMIG

Effects of other drugs, drug classes and over-the-counter products on ZOMIG

The following medications may interact with ZOMIG:

  • If co-administered with cimetidine: Maximum single dose of 2.5 mg, not to exceed 5 mg in any 24-hour period
Who makes ZOMIG?

Who makes ZOMIG?


Is ZOMIG safe in pregnancy?

Is ZOMIG safe in pregnancy?

Based on animal data, ZOMIG may cause fetal harm. You should talk to your healthcare provider before taking this medication if you are pregnant. ZOMIG should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.


What to do if you missed your ZOMIG dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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