ZOLOFT
Used for Depression and Anxiety
NowPatient can significantly lower the cost* of your prescription medication by providing free access to drug coupons, savings cards, patient assistance programs and other out of pocket discount programs. Whether you’re insured, uninsured, or underinsured, we empower you with transparency and cost-saving tools to make your ZOLOFT more affordable.
Manufactured by Viatris Specialty LLC
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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ZOLOFT key facts
What is ZOLOFT?
ZOLOFT is the brand name for sertraline and is available as an oral tablet and solution.
What dosages is ZOLOFT available in?
ZOLOFT is available as a 25 mg, 50 mg, and 100 mg oral tablet and a 20 mg/ml oral solution.
What is ZOLOFT used for?
ZOLOFT is a SSRI and is used for the following:
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Premenstrual dysphoric disorder (PMDD)
- Social anxiety disorder (SAD)
How does ZOLOFT work?
ZOLOFT is a selective serotonin reuptake inhibitor (SSRI). It works by raising the levels of serotonin, an important chemical in your brain that’s involved with regulating your mood and anxiety.
How do I take ZOLOFT?
ZOLOFT is dosed as follows:
Adults
- Depression, PD, OCD, PTSD, SAD: The typical starting dose ranges from 25 mg to 50 mg by mouth daily. The typical maintenance dose ranges from 50 mg to 200 mg daily, depending on your condition
- PMDD: The typical starting dose is 50 mg by mouth daily. Your psychiatrist might ask you to take this medication daily throughout your menstrual cycle (up to 150 mg daily), or to only take it daily starting 2 weeks before your period begins and stopping when your period ends (up to 100 mg daily)
Children (age 6 years and older)
- OCD: The typical starting dose ranges from 25 mg to 50 mg by mouth daily, depending on your child’s age. The typical maintenance dose ranges from 50 mg to 200 mg daily
Your physician will determine your dose based on your age and medical condition. Your dose might be different if you have liver problems.
Is it safe for me to take ZOLOFT?
ZOLOFT is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication any of the following apply to you:
- Currently take or have taken a monoamine oxidase inhibitor (MAOI), linezolid (Zyvox), or methylene blue (ProvayBlue) in the last 14 days
- Taking pimozide
- Taking disulfiram (ZOLOFT liquid only)
ZOLOFT Common Side Effects
Common side effects of ZOLOFT:
- Nausea
- Diarrhea
- Difficulty sleeping
- Dry mouth
- Sleepiness
ZOLOFT Serious Side Effects
Serious side effects are rare with ZOLOFT. Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts or behaviors
- Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, distress, hallucinations, coma
- Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
- Severe bleeding: bruising that doesn’t improve, black-colored stools, pink or red-colored urine, coughing up or vomiting blood, or unusual bleeding from the nose or gums
- Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren’t real), seizures, unconsciousness
Effects of other drugs, drug classes and over-the-counter products on ZOLOFT
The following medications may interact with ZOLOFT:
- Protein-bound drugs: Monitor for adverse reactions and reduce dosage of ZOLOFT or other protein-bound drugs (e.g., warfarin) as warranted
- CYP2D6 substrates: Reduce dosage of drugs metabolized by CYP2D6
Who makes ZOLOFT?
Viatris Specialty LLC
Is ZOLOFT safe in pregnancy?
ZOLOFT use in the third trimester may increase risk for persistent pulmonary hypertension and withdrawal in the neonate. You and your doctor will have to decide if you should take ZOLOFT while you are pregnant or if you plan to become pregnant. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants during pregnancy. Healthcare providers should encourage patients to enroll by calling the National Pregnancy Registry for Antidepressants at 1-866-961-2388 or visiting online at women’s health
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my ZOLOFT prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your ZOLOFT prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient ZOLOFT savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient ZOLOFT savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for ZOLOFT | Canadian Prescription Savings* for ZOLOFT | ZOLOFT Drug Coupon* | ZOLOFT Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of ZOLOFT?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for ZOLOFT | Canadian Prescription Savings* for ZOLOFT | ZOLOFT Drug Coupon* | ZOLOFT Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the ZOLOFT savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the ZOLOFT drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for ZOLOFT, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the ZOLOFT prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, ZOLOFT is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed ZOLOFT for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the ZOLOFT prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the ZOLOFT prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for ZOLOFT
If you are having trouble paying for your ZOLOFT medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for ZOLOFT you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- ZOLOFT is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers ZOLOFT
- If ZOLOFT is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for ZOLOFT
If you are having trouble paying for your ZOLOFT medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for ZOLOFT you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers ZOLOFT
- If ZOLOFT is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for ZOLOFT
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your ZOLOFT treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for ZOLOFT you will need to meet the following criteria:
- You must be currently insured and have coverage for ZOLOFT
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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