Home
/
Medications
/
ZOFRAN ODT

ZOFRAN ODT

Are you tired of high medication costs? Our service offers unbeatable savings on your ZOFRAN ODT prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by GlaxoSmithKline

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

Start Saving Today!

Lower the cost of your ZOFRAN ODT prescription

You can lower cost of your ZOFRAN ODT using one of the 4 following drug savings programs
  • Qualified

    NowPatient's Rx Advantage card is a simple & convenient way to save money on your ZOFRAN ODT

    Rx Advantage Card

    Save up to 90%

  • Available

    N/A
    Manufactured by
    N/A
    Powered by
    Buy your ZOFRAN ODT without insurance from Canada at discounts of up to 90% using NowPatient's Canadian Prescription savings program.

    Canadian Prescription Savings

  • Unavailable

    Obtain your ZOFRAN ODT for as little as $0 per fill. Suitable for insured individuals only.

    Drug Coupons

    Unavailable
  • Unavailable

    Obtain your ZOFRAN ODT at no cost. Suitable for insured, underinsured and uninsured individuals

    Patient Assistance Programs

    Unavailable
scrollable

ZOFRAN ODT Uses, Side Effects, Interactions, Warnings & Dosing

What is ZOFRAN ODT?

What is ZOFRAN ODT?

ZOFRAN ODT is the brand name for ondansetron and is available as an orally disintegrating tablet.

What dosages is ZOFRAN ODT available in?

What dosages is ZOFRAN ODT available in?

ZOFRAN ODT is available as a 4 mg and 8 mg orally disintegrating tablet.

What is ZOFRAN ODT used for?

What is ZOFRAN ODT used for?

ZOFRAN ODT is an antiemetic and is used for the:
Prevention of nausea and vomiting due to cancer medications (chemotherapy) or radiation therapy
Prevention of nausea and vomiting after surgery

How does ZOFRAN ODT work?

How does ZOFRAN ODT work?

ZOFRAN ODT is an antiemetic medication. It works by blocking the actions of serotonin in the part of your brain that causes nausea and vomiting. This helps you feel less nauseous and less of an urge to vomit.

How do I take ZOFRAN ODT?

How do I take ZOFRAN ODT?

ZOFRAN ODT is dosed as follows:
Adults
Prevention of nausea and vomiting from chemotherapy: Your oncologist will determine your dose based on how likely it is for your chemotherapy medications to cause nausea and vomiting.
High-risk chemotherapy: The typical dose is 24 mg as a single dose, taken by mouth 30 minutes before the start of chemotherapy.
Medium-risk chemotherapy: The typical dose is 8 mg as a single dose, taken by mouth 30 minutes before the start of chemotherapy. Take another 8 mg dose by mouth 8 hours after the first dose. After that, take an 8 mg dose by mouth every 12 hours for 1 to 2 days after completing chemotherapy.
Prevention of nausea and vomiting from radiation therapy: The typical dose is 8 mg as a single dose, taken by mouth 1 to 2 hours before radiation therapy. Depending on the type and location of radiation therapy, you might need to take additional 8 mg doses by mouth every 8 hours for 1 to 2 days after completing radiation.
Prevention of nausea and vomiting after surgery: The typical dose is 16 mg as a single dose, taken by mouth 1 hour before receiving anesthesia.

Children (age 12 to under 18)
Prevention of nausea and vomiting from chemotherapy: The typical dose is 8 mg as a single dose, taken by mouth 30 minutes before the start of chemotherapy. Take another 8 mg dose by mouth 8 hours after the first dose. After that, take 8 mg by mouth every 12 hours for 1 to 2 days after completing chemotherapy.

Children (age 4 to under 12)
Prevention of nausea and vomiting from chemotherapy: The typical dose is 4 mg as a single dose, taken by mouth 30 minutes before the start of chemotherapy. Take another 4 mg dose by mouth 4 hours and 8 hours after the first dose. After that, take 4 mg by mouth every 8 hours for 1 to 2 days after completing chemotherapy.

ZOFRAN is also available as an injection through the veins (IV) or into the muscle (IM) administered by a healthcare professional (HCP) for certain situations.

Is it safe for me to take ZOFRAN ODT?

Is it safe for me to take ZOFRAN ODT?

ZOFRAN ODT is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are also taking apomorphine (Apokyn) due to risk of severely low blood pressure and loss of consciousness.

ZOFRAN ODT Common Side Effects

ZOFRAN ODT Common Side Effects

Common side effects of ZOFRAN ODT:

  • Headache
  • Fatigue
  • Constipation
  • Diarrhea
ZOFRAN ODT Serious Side Effects

ZOFRAN ODT Serious Side Effects

Serious side effects are rare with ZOFRAN ODT. Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reactions: hives; trouble breathing; swelling of your face, lips, tongue, or throat
  • Abnormal heart rhythm: chest pounding, irregular heart beat, chest pain, short of breath, feeling faint or lightheaded
  • Heart attack
  • Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness or twitching, uncoordinated movement, distress, hallucinations
Effects of other drugs, drug classes and over-the-counter products on ZOFRAN ODT

Effects of other drugs, drug classes and over-the-counter products on ZOFRAN ODT

The following medications may interact with ZOFRAN ODT:

  • Serotonergic Drugs: Serotonin syndrome (including altered mental status, autonomic instability, and neuromuscular symptoms) has been described following the concomitant use of 5-HT3 receptor antagonists and other serotonergic drugs including selective serotonin reuptake inhibitors (SSRIs) and serotonin and noradrenaline reuptake inhibitors (SNRIs)
  • Drugs Affecting Cytochrome P-450 Enzymes: In patients treated with potent inducers of CYP3A4 (i.e., phenytoin, carbamazepine, and rifampin), the clearance of ondansetron was significantly increased and ondansetron blood concentrations were decreased However, on the basis of available data, no dosage adjustment for ZOFRAN ODT is recommended for patients on these drugs
Who makes ZOFRAN ODT?

Who makes ZOFRAN ODT?

GlaxoSmithKline

Is ZOFRAN ODT safe in pregnancy?

Is ZOFRAN ODT safe in pregnancy?

It is not known if ZOFRAN ODT will harm your unborn baby. You and your doctor will have to decide if you should take ZOFRAN ODT while you are pregnant or if you plan to become pregnant.

What is the generic name for ZOFRAN ODT?

What is the generic name for ZOFRAN ODT?

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
dollar sign

Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Now Patient Data Security

Data Security

Our Commitment to You.

Find out moreNow Patient Data SecurityNow Patient Data Security

WHY WE BUILT NOWPATIENT

To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.

Download our app today

A laptop screen displays a dashboard with various health metrics and notifications. Widgets include drug coupons, home health testing, genetic risk, diabetes risk, BMI, pollen meter, and air quality.

Your Questions Answered

For your peace of mind, we can answer your questions quickly

Frequently Asked Questions

Find your answers