Key facts about Zinplava
What is Zinplava?
Zinplava is the brand name for bezlotoxumab and is available as an IV injection.
What dosages is Zinplava available in?
Zinplava is available as a 1,000 mg/40 mL (25 mg/mL) solution for IV injection.
What is Zinplava used for?
Zinplava is a biologic and is used to treat prevention of another C. diff infection (CDI) in high-risk adults who are taking antibiotics for CDI.
How does Zinplava work?
Zinplava is an antibody (a type of protein). It attaches to a toxin that the C. diff bacteria releases into your body and neutralizes it.
How do I take Zinplava?
Zinplava is typically dosed as 10 mg/kg of body weight given as a single injection into the veins (intravenous, or IV) over 1 hour.
Is it safe for me to take Zinplava?
Zinplava is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Zinplava Common Side Effects
Common side effects of Zinplava:
- Nausea
- Fever
- Headache
Zinplava Serious Side Effects
Serious side effects are rare with Zinplava. Contact your healthcare provider immediately if you experience any of the following.
- Heart failure: shortness of breath, wheezing, swelling, tired, confusion, faster heart rate
Effects of other drugs, drug classes and over-the-counter products on Zinplava
Since Zinplava is eliminated by catabolism, no metabolic drug-drug interactions are expected.
Who makes Zinplava?
Merck & Co., Inc.
Is Zinplava safe in pregnancy?
It is not known if Zinplava can harm your unborn baby. Zinplava should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
