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Bezlotoxumab is available as a 1,000 mg/40 mL (25 mg/mL) solution for IV injection.

Bezlotoxumab is a biologic and is used to treat prevention of another C. diff infection (CDI) in high-risk adults who are taking antibiotics for CDI.

Bezlotoxumab is an antibody (a type of protein). It attaches to a toxin that the C. diff bacteria releases into your body and neutralizes it.

Bezlotoxumab is typically dosed as 10 mg/kg of body weight given as a single injection into the veins (intravenous, or IV) over 1 hour.

Bezlotoxumab is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Bezlotoxumab:

• Nausea
• Fever
• Headache

Serious side effects are rare with Bezlotoxumab. Contact your healthcare provider immediately if you experience any of the following.

• Heart failure: shortness of breath, wheezing, swelling, tired, confusion, faster heart rate

Since Bezlotoxumab is eliminated by catabolism, no metabolic drug-drug interactions are expected.

Various FDA-approved generic manufacturers

It is not known if Bezlotoxumab can harm your unborn baby. Bezlotoxumab should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.

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