Key facts about Bezlotoxumab
What dosages is Bezlotoxumab available in?
Bezlotoxumab is available as a 1,000 mg/40 mL (25 mg/mL) solution for IV injection.
What is Bezlotoxumab used for?
Bezlotoxumab is a biologic and is used to treat prevention of another C. diff infection (CDI) in high-risk adults who are taking antibiotics for CDI.
How does Bezlotoxumab work?
Bezlotoxumab is an antibody (a type of protein). It attaches to a toxin that the C. diff bacteria releases into your body and neutralizes it.
How do I take Bezlotoxumab?
Bezlotoxumab is typically dosed as 10 mg/kg of body weight given as a single injection into the veins (intravenous, or IV) over 1 hour.
Is it safe for me to take Bezlotoxumab?
Bezlotoxumab is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Bezlotoxumab Common Side Effects
Common side effects of Bezlotoxumab:
- Nausea
- Fever
- Headache
Bezlotoxumab Serious Side Effects
Serious side effects are rare with Bezlotoxumab. Contact your healthcare provider immediately if you experience any of the following.
- Heart failure: shortness of breath, wheezing, swelling, tired, confusion, faster heart rate
Effects of other drugs, drug classes and over-the-counter products on Bezlotoxumab
Since Bezlotoxumab is eliminated by catabolism, no metabolic drug-drug interactions are expected.
Who makes Bezlotoxumab?
Various FDA-approved generic manufacturers
Is Bezlotoxumab safe in pregnancy?
It is not known if Bezlotoxumab can harm your unborn baby. Bezlotoxumab should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.













