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Ziana is the brand name for clindamycin phosphate/tretinoin and is available as a topical gel.

Ziana is available as a topical gel containing clindamycin phosphate 1.2% and tretinoin 0.025%.

Ziana is a lincosamide antibiotic / retinoic acid derivative and is used to treat acne.

Ziana is a combination of two medications that treat acne. Clindamycin is a lincosamide antibiotic that kills acne-causing bacteria on the skin. Tretinoin is a retinoic acid derivative, which is related to vitamin A. It promotes healthy skin growth and lowers the amount of oil on your skin.

Ziana is dosed as follows:

• Use a pea-sized amount of Ziana, and gently rub it over the entire face once a day at bedtime. Do not apply it to the eyes, lips, or inside of the nose

Ziana is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have regional enteritis, ulcerative colitis, or history of antibiotic-associated colitis.

Common side effects of Ziana:

• Skin redness
• Scaly skin
• Itchy skin

Serious side effects are rare with Ziana. Contact your healthcare provider immediately if you experience any of the following.

• Allergic reactions
• Severe diarrhea

The following medications may interact with Ziana:

• Concomitant use of topical medications with a strong drying effect can increase skin irritation. Use with caution
• Ziana Gel should not be used in combination with erythromycin-containing products because of its clindamycin component

Bausch Health

It is not known if Ziana will harm your unborn baby. Ziana should be given to a pregnant woman only if clearly needed.

• Clindamycin Phosphate/Tretinoin