ZELAPAR ODT
NowPatient helps you obtain your ZELAPAR ODT prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by Bausch Health
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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ZELAPAR ODT key facts
What is ZELAPAR ODT?
ZELAPAR ODT is the brand name for selegiline hydrochloride and is available as an orally disintegrating tablet.
What dosages is ZELAPAR ODT available in?
ZELAPAR ODT is available as a 1.25 mg orally disintegrating tablet.
What is ZELAPAR ODT used for?
ZELAPAR ODT is a MAO-B inhibitor and is used to relieve “wearing-off” symptoms in people with Parkinson’s disease who are taking combination medications containing carbidopa and levodopa (e.g., Sinemet (carbidopa / levodopa), Rytary (carbidopa / levodopa)).
How does ZELAPAR ODT work?
ZELAPAR ODT is a monoamine oxidase type B (MAO-B) inhibitor. MAO-B is a protein in your brain that breaks down dopamine. Low levels of dopamine in your brain cause symptoms of Parkinson’s disease (PD). It’s not fully understood how selegiline works to relieve your PD symptoms. It’s thought that the medication blocks MAO-B to prevent dopamine from being broken down so that dopamine can stay in your brain longer. This helps control your PD symptoms.
How do I take ZELAPAR ODT?
ZELAPAR ODT is dosed as follows:
- Regular tablets and capsules: The typical dose is 5 mg by mouth at breakfast and 5 mg at lunch. Don’t take more than 10 mg of selegiline per day. After 2 to 3 days of taking the medication, your provider might prescribe a lower dose of carbidopa/levodopa, depending on how you respond to selegiline
- Quick-dissolving tablets, also known as orally disintegrating tablets (ODTs): ZELAPAR is the brand name for the ODT form of selegiline. The typical starting dose is 1.25 mg by mouth before breakfast every day for at least 6 weeks. If needed, the dose can be raised to 2.5 mg before breakfast after 6 weeks of taking the starting dose. Don’t take more than 2.5 mg of ZELAPAR per day. Your dose may differ if you have liver problems
Is it safe for me to take ZELAPAR ODT?
ZELAPAR ODT is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are using the following drugs: opioid drugs (e.g., meperidine, tramadol, methadone), MAO inhibitors including selective MAO-B inhibitors, dextromethorphan, St. John’s wort, and cyclobenzaprine.
ZELAPAR ODT Common Side Effects
Common side effects of ZELAPAR ODT:
- Nausea
- Dizziness
- General body pain
- Headache
- Trouble sleeping
- Runny nose
- Involuntary movements
- Skin irritation
- Back pain
- Heartburn
- Inflamed or sore mouth
ZELAPAR ODT Serious Side Effects
Serious side effects are rare with ZELAPAR ODT. Contact your healthcare provider immediately if you experience any of the following.
- Serotonin syndrome: Hallucinations, coma, seizures, confusion, restlessness, fainting, shivering, sweating, high fevers, headache, racing heart, high blood pressure, diarrhea, muscle stiffness or twitching, tremor
- Neuroleptic malignant syndrome (NMS): Very high fevers, irregular pulse, sweating, muscle stiffness, confusion, changes in blood pressure
- Extremely high blood pressure: Seizures, severe chest pain, severe headache, confusion, blurred vision, anxiety
Effects of other drugs, drug classes and over-the-counter products on ZELAPAR ODT
The following medications may interact with ZELAPAR ODT:
- Opioid Drugs: Because serious, sometimes fatal reactions have been precipitated with concomitant use of opioid drugs (e.g., meperidine and its derivatives, methadone, or tramadol) and MAOIs, including selective MAO-B inhibitors, concomitant use of these drugs with ZELAPAR is contraindicated. At least 14 days should elapse between discontinuation of ZELAPAR and initiation of treatment with these drugs
- Dextromethorphan: The combination of MAO inhibitors and dextromethorphan has been reported to cause brief episodes of psychosis or bizarre behavior. Therefore, in view of ZELAPAR’s MAO inhibitory activity, dextromethorphan should not be used concomitantly with ZELAPAR.
- MAO Inhibitors: ZELAPAR is contraindicated for concomitant use with other drugs in the MAOI class or
- other drugs that are potent inhibitors of monoamine oxidase (including linezolid, an oxazolidinone antibacterial, which also has reversible nonselective MAO inhibition activity) because of the increased risk for hypertensive crisis. At least 14 days should elapse between discontinuation of ZELAPAR and initiation of treatment with other MAOIs.
- Sympathomimetic Medications: Uncontrolled hypertension, including hypertensive crisis, has been reported when taking the recommended dose of swallowed selegiline and a sympathomimetic medication
- Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors
- Severe toxicity has also been reported in patients receiving the combination of tricyclic antidepressants and swallowed selegiline, or selective serotonin reuptake inhibitors and swallowed selegiline
Who makes ZELAPAR ODT?
Bausch Health
Is ZELAPAR ODT safe in pregnancy?
ZELAPAR ODT may harm your unborn baby, based on animal data. Tell your healthcare provider if you are pregnant or think you are pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my ZELAPAR ODT prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your ZELAPAR ODT prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient ZELAPAR ODT savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient ZELAPAR ODT savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for ZELAPAR ODT | Canadian Prescription Savings* for ZELAPAR ODT | ZELAPAR ODT Drug Coupon* | ZELAPAR ODT Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of ZELAPAR ODT?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for ZELAPAR ODT | Canadian Prescription Savings* for ZELAPAR ODT | ZELAPAR ODT Drug Coupon* | ZELAPAR ODT Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the ZELAPAR ODT savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the ZELAPAR ODT drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for ZELAPAR ODT, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the ZELAPAR ODT prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, ZELAPAR ODT is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed ZELAPAR ODT for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the ZELAPAR ODT prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the ZELAPAR ODT prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for ZELAPAR ODT
If you are having trouble paying for your ZELAPAR ODT medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for ZELAPAR ODT you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- ZELAPAR ODT is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers ZELAPAR ODT
- If ZELAPAR ODT is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for ZELAPAR ODT
If you are having trouble paying for your ZELAPAR ODT medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for ZELAPAR ODT you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers ZELAPAR ODT
- If ZELAPAR ODT is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for ZELAPAR ODT
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your ZELAPAR ODT treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for ZELAPAR ODT you will need to meet the following criteria:
- You must be currently insured and have coverage for ZELAPAR ODT
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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