YONDELIS
Used for Cancer
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Manufactured by Janssen Pharmaceuticals
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YONDELIS Uses, Side Effects, Interactions, Warnings & Dosing
What is YONDELIS?
YONDELIS is the brand name for trabectedin and is available as an injection for IV use.
What dosages is YONDELIS available in?
YONDELIS is available as a 1 mg injection for IV use.
What is YONDELIS used for?
YONDELIS is an alkylating agent and is used for the following:
Liposarcoma that has spread or can’t be removed
Leiomyosarcoma that has spread or can’t be removed
How does YONDELIS work?
YONDELIS is an alkylating agent and works by slowing down the growth of cancer cells.
How do I take YONDELIS?
YONDELIS is typically dosed as 1.5 mg/m2 body surface area as a 24-hour intravenous infusion, every 3 weeks through a central venous line. Your dose may be lower if you have liver problems.
Is it safe for me to take YONDELIS?
YONDELIS is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
YONDELIS Common Side Effects
Common side effects of YONDELIS:
- Nausea
- Fatigue
- Vomiting
- Constipation
- Decreased appetite
- Diarrhea
- Peripheral edema
- Shortness of breath
- Headache
YONDELIS Serious Side Effects
Serious side effects are rare with YONDELIS. Contact your doctor if you experience any of the following.
- Severe muscle problems (rhabdomyolysis)
- Severe infections
- Liver or heart problems
- Leakage of YONDELIS out of your vein during the infusion
Effects of other drugs, drug classes and over-the-counter products on YONDELIS
The following medications may interact with YONDELIS:
- CYP3A inhibitors: Avoid concomitant strong CYP3A inhibitors
- • CYP3A inducers: Avoid concomitant strong CYP3A inducers
Who makes YONDELIS?
Janssen Pharmaceuticals
Is YONDELIS safe in pregnancy?
Based on its mechanism of action, YONDELIS can cause fetal harm when administered to a pregnant woman. If you can become pregnant, you should use effective contraception during therapy and for at least 2 months after the last dose of YONDELIS. Advise males with female partners of reproductive potential to use effective contraception during therapy and for at least 5 months after the last dose of YONDELIS.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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