XTANDI
Used for Cancer
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Manufactured by Astellas Pharma
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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XTANDI Uses, Side Effects, Interactions, Warnings & Dosing
What is XTANDI?
XTANDI is the brand name for enzalutamide and is available as an oral tablet or capsule.
What dosages is XTANDI available in?
XTANDI is available as a 40 mg oral capsule and a 40 mg and 80 mg oral tablet.
What is XTANDI used for?
XTANDI is an androgen receptor inhibitor that is used to treat advanced or metastatic prostate cancer.
How does XTANDI work?
XTANDI is an androgen receptor inhibitor (antiandrogen), a type of hormone therapy that works by blocking testosterone from binding to prostate cancer cells. Without testosterone, cancer cells won’t have the fuel they need to grow or spread.
How do I take XTANDI?
The typical dose is XTANDI 160 mg by mouth once a day.
Is it safe for me to take XTANDI?
XTANDI is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
XTANDI Common Side Effects
Common side effects of XTANDI:
- Weakness or fatigue
- Back pain
- Hot flashes
- Constipation
- Diarrhea
- Joint pain
- Feeling less hungry
- High blood pressure
XTANDI Serious Side Effects
Serious side effects are rare with XTANDI. Contact your healthcare provider immediately if you experience any of the following.
- Seizures
- New confusion, seizures, or sudden changes in mood or behavior: severe headaches, visual changes, difficulty staying awake, dizziness, trouble speaking
- Heart problems: chest pain, racing heartbeat, shortness of breath, arm or shoulder pain, swelling of your legs or feet, sudden weight gain, sweating, fatigue, dizziness, nausea or vomiting
Effects of other drugs, drug classes and over-the-counter products on XTANDI
The following medications may interact with XTANDI:
- Strong CYP2C8 Inhibitors: Avoid strong CYP2C8 inhibitors. If coadministration cannot be avoided, reduce the dosage of XTANDI
- Strong CYP3A4 Inducers: Avoid strong CYP3A4 inducers. If coadministration cannot be avoided, increase the dosage of XTANDI
- Avoid coadministration with certain CYP3A4, CYP2C9, or CYP2C19 substrates for which a minimal decrease in
- concentration may lead to therapeutic failure of the substrate. In cases where active metabolites are formed, there may be increased exposure to the active metabolites
Who makes XTANDI?
Astellas Pharma
Is XTANDI safe in pregnancy?
XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage). Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose of XTANDI. Males must use a condom during sex with a pregnant female.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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