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MEDICAL INFORMATION
Xofigo Key Facts
What is Xofigo?
Xofigo is the brand name for radium Ra 223 dichloride IV injections.
What dosages is Xofigo available in?
Xofigo is available as a single-dose vial at a concentration of 1,100 kBq/mL (30 microcurie/mL) at the reference date with a total radioactivity of 6,600 kBq/vial (178 microcurie/vial) at the reference date.
What is Xofigo used for?
Xofigo is a radiopharmaceutical that is used for metastatic, castration-resistant prostate cancer that’s spread to the bone only and causing symptoms.
How does Xofigo work?
Xofigo is a radiopharmaceutical. It’s made of the radioactive chemical radium-223. Radium-223 acts like calcium in the body and is taken into the bones. Advanced prostate cancer can sometimes spread to the bones. So when Xofigo is absorbed into the bone, the radioactivity damages the tumor cells there, stopping them from growing and spreading.
How do I take Xofigo?
Your treatment team will calculate your specific dose based on your body weight. The typical dose is 55 kBq/kg given as an infusion through the vein (IV) every 4 weeks for 6 doses. Note: kBq is a unit of radioactivity. Since this medication works by delivering radiation, the dose is described using units that measure radioactivity.
Is it safe for me to take Xofigo?
Xofigo is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Xofigo Common Side Effects
Common side effects of Xofigo:
- Low red blood cell counts
- Low white blood cells
- Nausea
- Low platelet count
- Diarrhea
Xofigo Serious Side Effects
Serious side effects are rare with Xofigo. Contact your healthcare provider immediately if you experience any of the following.
- Low blood cell counts: fever, chills, feeling very tired, dizziness, unusual bleeding or bruising
Effects of other drugs, drug classes and over-the-counter products on Xofigo
- There are no major drug interactions listed for Xofigo. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes Xofigo?
Bayer Healthcare
Is Xofigo safe in pregnancy?
XOFIGOBased on mechanism of action, Xofigo can cause
fetal harm when administered to a pregnant female. Inform your doctor immediately if you become pregnant while taking Xofigo.
What is the generic name for Xofigo?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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