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Radium Ra 223 Dichloride is available as a single-dose vial at a concentration of 1,100 kBq/mL (30 microcurie/mL) at the reference date with a total radioactivity of 6,600 kBq/vial (178 microcurie/vial) at the reference date.

Radium Ra 223 Dichloride is a radiopharmaceutical that is used for metastatic, castration-resistant prostate cancer that’s spread to the bone only and causing symptoms.

Radium Ra 223 Dichloride is a radiopharmaceutical. It’s made of the radioactive chemical radium-223. Radium-223 acts like calcium in the body and is taken into the bones. Advanced prostate cancer can sometimes spread to the bones. So when Radium Ra 223 Dichloride is absorbed into the bone, the radioactivity damages the tumor cells there, stopping them from growing and spreading.

Your treatment team will calculate your specific dose based on your body weight. The typical dose is 55 kBq/kg given as an infusion through the vein (IV) every 4 weeks for 6 doses. Note: kBq is a unit of radioactivity. Since this medication works by delivering radiation, the dose is described using units that measure radioactivity.

Radium Ra 223 Dichloride is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Radium Ra 223 Dichloride:

• Low red blood cell counts
• Low white blood cells
• Nausea
• Low platelet count
• Diarrhea

Serious side effects are rare with Radium Ra 223 Dichloride. Contact your healthcare provider immediately if you experience any of the following.

• Low blood cell counts: fever, chills, feeling very tired, dizziness, unusual bleeding or bruising

• There are no major drug interactions listed for Radium Ra 223 Dichloride. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Various FDA-approved generic manufacturers

radium Ra 223 dichlorideBased on mechanism of action, Radium Ra 223 Dichloride can cause
fetal harm when administered to a pregnant female. Inform your doctor immediately if you become pregnant while taking Radium Ra 223 Dichloride.

• Xofigo