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Vraylar is the brand name for cariprazine and is available as an oral capsule.

Vraylar is available as a 1.5 mg, 3 mg, 4.5 mg, and 6 mg oral capsule.

Vraylar is an atypical antipsychotic and is used for the following:

• Schizophrenia
• Manic or mixed episodes of bipolar I disorder
• Bipolar depression of bipolar I disorder
• Major depressive disorder (MDD), as an add-on medication

Vraylar is an atypical antipsychotic. The exact way it works isn’t well-understood. But it’s thought to make dopamine and serotonin levels more stable in your brain to help control your thoughts, mood, and behaviors.

Vraylar is typically dosed as follows:

• Schizophrenia and bipolar mania: The typical starting dose is 1.5 mg by mouth once a day. Your provider might raise your dose after a few days. The usual dosing range is 1.5 mg to 6 mg once a day
• Bipolar depression and MDD: The typical starting dose is 1.5 mg by mouth once a day. Your provider might raise your dose after 2 weeks. The usual dosing range is 1.5 mg to 3 mg once a day

Vraylar is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Vraylar:

• Uncontrolled muscle movements
• Headache
• Restlessness
• Trouble sleeping
• Constipation
• Nausea
• Stomach pain
• Toothache

Serious side effects are rare with Vraylar. Contact your healthcare provider immediately if you experience any of the following.

• Stroke: numbness or weakness typically on one side of the body, loss of balance, headache, blurred vision, difficulty speaking
• Neuroleptic malignant syndrome (NMS): high fever, sweating, confusion, stiffness, blood pressure changes
  Extremely high blood sugar levels: feeling very hungry or thirsty, urinating more often, stomach pain, weakness, fruity-smelling breath
• Uncontrolled muscle movements (tardive dyskinesia): involuntarily sticking out your tongue, puffing out your cheeks, puckering your mouth, lip smacking, chewing, and foot tapping
• Suicidal thoughts or behavior
• Seizures
• Dizzy or fainting spells that cause falls

The following medications may interact with Vraylar:

• Strong CYP3A4 inhibitors: Reduce Vraylar dosage by half
• CYP3A4 inducers: Concomitant use is not recommended

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Vraylar may harm your unborn baby. Taking Vraylar during your third trimester of pregnancy may cause your baby to have abnormal muscle movements or withdrawal
symptoms after birth. Talk to your healthcare provider about the risk to your unborn baby if you take Vraylar during pregnancy. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to
Vraylar during pregnancy. For more information, contact the National Pregnancy Registry for Atypical Antipsychotics at 1-866-961-2388 or visit women’s health 

• Cariprazine