Key facts about Vizimpro
What is Vizimpro?
Vizimpro is the brand name for dacomitinib and is available as an oral tablet.
What dosages is Vizimpro available in?
Vizimpro is available as a 15 mg, 30 mg, and 45 mg oral tablet.
What is Vizimpro used for?
Vizimpro is a kinase inhibitor that is used to treat metastatic non-small cell lung cancer (NSCLC) with changes in the EGFR gene.
How does Vizimpro work?
Vizimpro is a kinase inhibitor. It targets EGFR proteins made by these mutated EGFR genes. When EGFR is blocked by Vizimpro, the cancer cells can’t grow and spread as well.
How do I take Vizimpro?
Vizimpro is typically taken as 45 mg by mouth once daily.
Is it safe for me to take Vizimpro?
Vizimpro is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Vizimpro Common Side Effects
Common side effects of Vizimpro:
- Diarrhea
- Rash
- Nail infection
- Painful sores inside the mouth and throat
- Low red and white blood cell counts
- Low albumin levels
- Higher liver enzyme levels
- High blood sugar
- Low electrolyte levels
- Loss of appetite
- Dry skin
- Weight loss
- Hair loss
- Itchy skin
- Cough
Vizimpro Serious Side Effects
Serious side effects are rare with Vizimpro. Contact your healthcare provider immediately if you experience any of the following.
- Serious lung problems: dry cough, fever, trouble breathing, fast or shallow breathing, chest pain
Severe diarrhea
Effects of other drugs, drug classes and over-the-counter products on Vizimpro
The following medications may interact with Vizimpro:
- Proton Pump Inhibitors (PPIs): Avoid use with Vizimpro; use locally-acting antacids or H2-receptor antagonist; administer Vizimpro at least 6 hours before or 10 hours after H2-receptor antagonist
- CYP2D6 Substrates: Avoid concomitant use with Vizimpro where minimal increases in concentration of the CYP2D6 substrate may lead to serious or life-threatening toxicities
Who makes Vizimpro?
Pfizer Inc.
Is Vizimpro safe in pregnancy?
Vizimpro can harm your unborn baby. Females who are able to become pregnant:
- Your healthcare provider should do a pregnancy test before you start treatment with Vizimpro
- You should use effective birth control (contraception) during treatment and for at least 17 days after your last dose of Vizimpro. Talk to your healthcare provider about birth control methods that may be right for you during this time
- Tell your healthcare provider right away if you become pregnant during your treatment with Vizimpro
