Used for Cancer

View dacomitinib savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or dacomitinib Patient Assistance Program.

Programs are suitable for individuals who want to buy dacomitinib without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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    Save up to 90%

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    Drug Coupons

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Updated on 24 Apr 2024

Learn more about dacomitinib

What dosages is dacomitinib available in?

What dosages is dacomitinib available in?

dacomitinib is available as a 15 mg, 30 mg, and 45 mg oral tablet.

What is dacomitinib used for?

What is dacomitinib used for?

dacomitinib is a kinase inhibitor that is used to treat metastatic non-small cell lung cancer (NSCLC) with changes in the EGFR gene.

How does dacomitinib work?

How does dacomitinib work?

dacomitinib is a kinase inhibitor. It targets EGFR proteins made by these mutated EGFR genes. When EGFR is blocked by dacomitinib, the cancer cells can’t grow and spread as well.

How do I take dacomitinib?

How do I take dacomitinib?

dacomitinib is typically taken as 45 mg by mouth once daily.

Is it safe for me to take dacomitinib?

Is it safe for me to take dacomitinib?

dacomitinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

dacomitinib Common Side Effects

dacomitinib Common Side Effects

Common side effects of dacomitinib:

  • Diarrhea
  • Rash
  • Nail infection
  • Painful sores inside the mouth and throat
  • Low red and white blood cell counts
  • Low albumin levels
  • Higher liver enzyme levels
  • High blood sugar
  • Low electrolyte levels
  • Loss of appetite
  • Dry skin
  • Weight loss
  • Hair loss
  • Itchy skin
  • Cough
dacomitinib Serious Side Effects

dacomitinib Serious Side Effects

Serious side effects are rare with dacomitinib. Contact your healthcare provider immediately if you experience any of the following.

  • Serious lung problems: dry cough, fever, trouble breathing, fast or shallow breathing, chest pain
    Severe diarrhea
Effects of other drugs, drug classes and over-the-counter products on dacomitinib

Effects of other drugs, drug classes and over-the-counter products on dacomitinib

The following medications may interact with dacomitinib:

  • Proton Pump Inhibitors (PPIs): Avoid use with dacomitinib; use locally-acting antacids or H2-receptor antagonist; administer dacomitinib at least 6 hours before or 10 hours after H2-receptor antagonist
  • CYP2D6 Substrates: Avoid concomitant use with dacomitinib where minimal increases in concentration of the CYP2D6 substrate may lead to serious or life-threatening toxicities
Who makes dacomitinib?

Who makes dacomitinib?

Various FDA-approved generic manufacturers

Is dacomitinib safe in pregnancy?

Is dacomitinib safe in pregnancy?

dacomitinib can harm your unborn baby. Females who are able to become pregnant:

  • Your healthcare provider should do a pregnancy test before you start treatment with dacomitinib
  • You should use effective birth control (contraception) during treatment and for at least 17 days after your last dose of dacomitinib. Talk to your healthcare provider about birth control methods that may be right for you during this time
  • Tell your healthcare provider right away if you become pregnant during your treatment with dacomitinib

What to do if you missed your dacomitinib dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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