vismodegib
Used for Cancer
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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vismodegib Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is vismodegib available in?
vismodegib is available as a 150 mg oral capsule.
What is vismodegib used for?
vismodegib is a hedgehog pathway inhibitor that is used to treat basal cell carcinoma that has spread to other parts of the body (metastatic) or that can’t be removed by surgery.
How does vismodegib work?
vismodegib is a Hedgehog pathway inhibitor, meaning it blocks the Hedgehog pathway. It treats skin cancer by turning this pathway off so that the cancer cells can’t grow or spread as well.
How do I take vismodegib?
The usual dose is 150 mg by mouth once a day.
Is it safe for me to take vismodegib?
vismodegib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
vismodegib Common Side Effects
Common side effects of vismodegib:
- Muscle spasms
- Hair loss
- Taste changes
- Weight loss
- Tiredness
- Nausea
- Diarrhea
- Lower appetite
- Constipation
- Joint pain
vismodegib Serious Side Effects
Serious side effects are rare with vismodegib. Contact your healthcare provider immediately if you experience any of the following.
- Serious skin reactions: painful blisters, skin wounds, peeling skin, fever, sore throat, body aches
Effects of other drugs, drug classes and over-the-counter products on vismodegib
- There are no major drug interactions listed for vismodegib. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes vismodegib?
Various FDA-approved generic manufacturers
Is vismodegib safe in pregnancy?
vismodegib can cause your baby to die before it is born (be stillborn) or cause your baby to have severe birth
defects. For females who can become pregnant:
Your healthcare provider will do a pregnancy test within 7 days before you start taking vismodegib. In order to avoid pregnancy, you should use birth control during treatment and for 24 months after your final dose of vismodegib. Talk with your healthcare provider about what birth control method is right for you during this time. Tell your healthcare provider right away if you become pregnant or think that you may be pregnant.
For males:
vismodegib is present in semen. Do not donate semen while you are taking vismodegib and for 3 months after
your final dose.
You should always use a condom, even if you have had a vasectomy, during sex with female partners who are
pregnant or who are able to become pregnant, during treatment with vismodegib and for 3 months after your final
dose to protect your female partner from being exposed to vismodegib. Tell your healthcare provider right away if your partner becomes pregnant or thinks she is pregnant while you are taking vismodegib. Pregnancy Exposure Registry:
There is a Pregnancy Exposure Registry for females taking vismodegib who become pregnant. The purpose of this
registry is to monitor the health of you and your unborn baby. If you think that you or your female partner may have
been exposed to vismodegib during pregnancy, talk to your healthcare provider right away. If you become pregnant
during treatment with vismodegib, you or your healthcare provider should report your pregnancy to Genentech at 1-888-835-2555.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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