velaglucerase alfa
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Manufactured by various FDA-approved generic manufacturers.
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velaglucerase alfa Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is velaglucerase alfa available in?
velaglucerase alfa is available as a 200 Units and 400 Units single-use vial for IV infusion.
What is velaglucerase alfa used for?
velaglucerase alfa is a hydrolytic lysosomal glucocerebrosidase-specific enzyme and is used to treat type 1 Gaucher disease in adults and children 4 years of age or older.
How does velaglucerase alfa work?
velaglucerase alfa is a modified (lab-made) version of the enzyme glucocerebrosidase that is normally found in the body. People with Gaucher disease don’t have enough of this enzyme, which breaks down a fatty substance called glucocerebroside. As a result, there are higher levels of glucocerebroside in the body, and it can build up in the spleen, liver, and bones. velaglucerase alfa works as an enzyme replacement for glucocerebrosidase and helps your body break down glucocerebroside.
How do I take velaglucerase alfa?
velaglucerase alfa is an intravenous (IV) infusion that is administered by a healthcare provider. The dose depends on your weight.
If you haven’t been treated before (treatment naive): In general, the typical starting dose is 60 units/kg once every other week.
If you’re switching from Cerezyme (imiglucerase): The usual starting dose of velaglucerase alfa (velaglucerase alfa) is the same dose of Cerezyme (imiglucerase) you were previously using.
Is it safe for me to take velaglucerase alfa?
velaglucerase alfa is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
velaglucerase alfa Common Side Effects
Common side effects of velaglucerase alfa:
- Headache
- Fever
- Dizziness
- Stomach pain
- Back pain
- Knee pain
- Fatigue
- Nausea
velaglucerase alfa Serious Side Effects
Serious side effects are rare with velaglucerase alfa. Contact your healthcare provider immediately if you experience any of the following.
Serious allergic reactions: throat tightness, trouble breathing, cough, itching or hives, flushing, swelling, chest pain, fast heartbeat, dizziness, fainting
Effects of other drugs, drug classes and over-the-counter products on velaglucerase alfa
No drug-drug interaction studies have been conducted with velaglucerase alfa. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes velaglucerase alfa?
Various FDA-approved generic manufacturers
Is velaglucerase alfa safe in pregnancy?
It is not known if velaglucerase alfa can harm your unborn baby.
velaglucerase alfa should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
What to do if you missed your velaglucerase alfa dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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