VPRIV
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Manufactured by Shire US Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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VPRIV Uses, Side Effects, Interactions, Warnings & Dosing
What is VPRIV?
VPRIV is the brand name for velaglucerase alfa and is available as an IV infusion.
What dosages is VPRIV available in?
VPRIV is available as a 200 Units and 400 Units single-use vial for IV infusion.
What is VPRIV used for?
VPRIV is a hydrolytic lysosomal glucocerebrosidase-specific enzyme and is used to treat type 1 Gaucher disease in adults and children 4 years of age or older.
How does VPRIV work?
VPRIV is a modified (lab-made) version of the enzyme glucocerebrosidase that is normally found in the body. People with Gaucher disease don’t have enough of this enzyme, which breaks down a fatty substance called glucocerebroside. As a result, there are higher levels of glucocerebroside in the body, and it can build up in the spleen, liver, and bones. VPRIV works as an enzyme replacement for glucocerebrosidase and helps your body break down glucocerebroside.
How do I take VPRIV?
VPRIV is an intravenous (IV) infusion that is administered by a healthcare provider. The dose depends on your weight.
If you haven’t been treated before (treatment naive): In general, the typical starting dose is 60 units/kg once every other week.
If you’re switching from Cerezyme (imiglucerase): The usual starting dose of Vpriv (velaglucerase alfa) is the same dose of Cerezyme (imiglucerase) you were previously using.
Is it safe for me to take VPRIV?
VPRIV is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
VPRIV Common Side Effects
Common side effects of VPRIV:
- Headache
- Fever
- Dizziness
- Stomach pain
- Back pain
- Knee pain
- Fatigue
- Nausea
VPRIV Serious Side Effects
Serious side effects are rare with VPRIV. Contact your healthcare provider immediately if you experience any of the following.
Serious allergic reactions: throat tightness, trouble breathing, cough, itching or hives, flushing, swelling, chest pain, fast heartbeat, dizziness, fainting
Effects of other drugs, drug classes and over-the-counter products on VPRIV
No drug-drug interaction studies have been conducted with VPRIV. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes VPRIV?
Shire US Inc.
Is VPRIV safe in pregnancy?
It is not known if VPRIV can harm your unborn baby.
VPRIV should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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