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Toremifene Citrate is available as a 60 mg oral tablet.

Toremifene Citrate is a type of hormone therapy used in the treatment of metastatic breast cancer in postmenopausal women with estrogen-receptor positive or unknown tumors.

Toremifene Citrate is a selective estrogen receptor modulator. Some breast cancers rely on the hormone estrogen to grow and are called hormone-receptor positive (HR+). Toremifene Citrate blocks estrogen from working on breast tissue. By doing this, cancer cells don’t have the fuel they need to grow, which stops breast cancer from growing and spreading.

The typical dose of Toremifene Citrate is 60 mg once daily.

Toremifene Citrate is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Hypersensitivity to the drug
• QT Prolongation
• Hypokalemia
• Hypomagnesemia

Common side effects of Toremifene Citrate:

• Hot flashes
• Sweating
• Nausea
• Vaginal discharge
• Cataracts
• Dry eyes

Serious side effects are rare with Toremifene Citrate. Contact your healthcare provider immediately if you experience any of the following:

• Abnormal heart rhythm: feel your heart beating, weakness, blurred vision, lightheadedness
• Cancers of the uterus: abnormal vaginal bleeding, vaginal discharge, or pain or pressure in the area below your belly button (pelvis)
• Blood clots in your veins or lungs: pain or swelling in your arms or legs, trouble breathing, chest pain, fast heartbeat

The following medications may interact with Toremifene Citrate:

• Drugs that decrease renal calcium excretion, likee thiazide diuretics
• Medications that prolong the QT interval
• Strong CYP3A4 inducers
• Strong CYP3A4 inhibitors
• CYP2C9 substrates with a narrow therapeutic index such as warfarin or
• Phenytoin

Various FDA-approved generic manufacturers

Toremifene Citrate may harm the fetus and increase the risk for pregnancy loss. Women should be advised not to become pregnant when taking this medication.

• Fareston