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Thyrogen is the brand name for thyrotropin alfa and is available as an intramuscular injection.

Thyrogen is available as 0.9 mg of thyrotropin alfa in a single-dose vial.

Thyrogen is a thyroid stimulating hormone that is used to check your body for the return of thyroid cancer after treatment. It is also used to help treat thyroid cancer.

Thyrogen works by measuring the level of a substance in your body (thyroglobulin) that is produced if cancer cells are present. For thyroid cancer, it helps thyroid tissue cells take up radioactive iodine, which slows or stops the spread of cancer cells.

A two-injection regimen is recommended:

• Thyrogen 0.9 mg is administered intramuscularly,
• Followed by a second 0.9 mg intramuscular injection 24 hours later.

Thyrogen is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Allergic reaction to any ingredient in the product

Common side effects of Thyrogen:

• Nausea
• Headache

Serious side effects are rare with Thyrogen. Contact your healthcare provider immediately if you experience any of the following:

Thyrogen-induced hyperthyroidism:

• Stroke
• Sudden rapid tumor enlargement

There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Sanofi-Aventis U.S.

Thyrogen may be used in combination with radioiodine (RAI). If it is administered with RAI, the combination regimen is contraindicated in pregnant women.

• Thyrotropin Alfa