taliglucerase alfa
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Manufactured by various FDA-approved generic manufacturers.
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taliglucerase alfa Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is taliglucerase alfa available in?
taliglucerase alfa is available as a 200 unit IV injection.
What is taliglucerase alfa used for?
taliglucerase alfa is a hydrolytic lysosomal glucocerebrosidase-specific enzyme and is used to treat type 1 Gaucher disease in adults and children 4 years of age or older.
How does taliglucerase alfa work?
taliglucerase alfa is a plant-based, modified (lab-made) version of the enzyme glucocerebrosidase that is normally found in the body. People with Gaucher disease don’t have enough of this enzyme, which breaks down a fatty substance called glucocerebroside. As a result, there are higher levels of glucocerebroside in the body, and it can build up in the spleen, liver, and bones. taliglucerase alfa works as an enzyme replacement for glucocerebrosidase and helps your body break down glucocerebroside.
How do I take taliglucerase alfa?
taliglucerase alfa is an intravenous (IV) infusion that is administered by a healthcare provider. The dose depends on your weight.
- If you haven’t been treated before (treatment naive): In general, the typical starting dose is 60 units/kg once every other week
- If you’re switching from Cerezyme (imiglucerase): The usual starting dose of taliglucerase alfa (taliglucerase alfa) is the same dose of Cerezyme (imiglucerase) you were previously on
Is it safe for me to take taliglucerase alfa?
taliglucerase alfa is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
taliglucerase alfa Common Side Effects
Common side effects of taliglucerase alfa:
- Headache
- Joint pain
- Arm or leg pain
- Fatigue
- Nausea
- Dizziness
taliglucerase alfa Serious Side Effects
Serious side effects are rare with taliglucerase alfa. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reactions: throat tightness or irritation, trouble breathing, cough, wheezing, itching or hives, flushing, swelling, chest pain or tightness, dizziness, fainting, nausea, vomiting
Effects of other drugs, drug classes and over-the-counter products on taliglucerase alfa
There are no major drug interactions listed for taliglucerase alfa. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes taliglucerase alfa?
Various FDA-approved generic manufacturers
Is taliglucerase alfa safe in pregnancy?
It is not known if taliglucerase alfa can harm your unborn baby. taliglucerase alfa should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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