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ELELYSO Uses, Side Effects, Interactions, Warnings & Dosing

What is ELELYSO?

What is ELELYSO?

ELELYSO is the brand name for taliglucerase alfa and is available as an injection for IV use.

What dosages is ELELYSO available in?

What dosages is ELELYSO available in?

ELELYSO is available as a 200 unit IV injection.

What is ELELYSO used for?

What is ELELYSO used for?

ELELYSO is a hydrolytic lysosomal glucocerebrosidase-specific enzyme and is used to treat type 1 Gaucher disease in adults and children 4 years of age or older.

How does ELELYSO work?

How does ELELYSO work?

ELELYSO is a plant-based, modified (lab-made) version of the enzyme glucocerebrosidase that is normally found in the body. People with Gaucher disease don’t have enough of this enzyme, which breaks down a fatty substance called glucocerebroside. As a result, there are higher levels of glucocerebroside in the body, and it can build up in the spleen, liver, and bones. ELELYSO works as an enzyme replacement for glucocerebrosidase and helps your body break down glucocerebroside.

How do I take ELELYSO?

How do I take ELELYSO?

ELELYSO is an intravenous (IV) infusion that is administered by a healthcare provider. The dose depends on your weight.

  • If you haven’t been treated before (treatment naive): In general, the typical starting dose is 60 units/kg once every other week
  • If you’re switching from Cerezyme (imiglucerase): The usual starting dose of Elelyso (taliglucerase alfa) is the same dose of Cerezyme (imiglucerase) you were previously on
Is it safe for me to take ELELYSO?

Is it safe for me to take ELELYSO?

ELELYSO is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

ELELYSO Common Side Effects

ELELYSO Common Side Effects

Common side effects of ELELYSO:

  • Headache
  • Joint pain
  • Arm or leg pain
  • Fatigue
  • Nausea
  • Dizziness
ELELYSO Serious Side Effects

ELELYSO Serious Side Effects

Serious side effects are rare with ELELYSO. Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reactions: throat tightness or irritation, trouble breathing, cough, wheezing, itching or hives, flushing, swelling, chest pain or tightness, dizziness, fainting, nausea, vomiting
Effects of other drugs, drug classes and over-the-counter products on ELELYSO

Effects of other drugs, drug classes and over-the-counter products on ELELYSO

There are no major drug interactions listed for ELELYSO. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Who makes ELELYSO?

Who makes ELELYSO?


Is ELELYSO safe in pregnancy?

Is ELELYSO safe in pregnancy?

It is not known if ELELYSO can harm your unborn baby. ELELYSO should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.


What to do if you missed your ELELYSO dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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