Key facts about Takhzyro
What is Takhzyro?
Takhzyro is the brand name for lanadelumab-flyo and is available as a subcutaneous injection.
What dosages is Takhzyro available in?
Takhzyro is available as one of the following:
- 150 mg/1 mL (150 mg/mL) solution in a single-dose prefilled syringe
300 mg/2 mL (150 mg/mL) solution in a single-dose prefilled syringe
300 mg/2 mL (150 mg/mL) solution in a single-dose vial
What is Takhzyro used for?
Takhzyro is a plasma kallikrein inhibitor and is used to prevent HAE attacks in people 12 years and older.
How does Takhzyro work?
Takhzyro is a monoclonal antibody that’s in a group of medications called plasma kallikrein inhibitors. It blocks the activity of a protein in your blood called plasma kallikrein. Plasma kallikrein is more active in people with hereditary angioedema (HAE) and raises the production of bradykinin, a substance that’s responsible for pain and swelling. By lowering plasma kallikrein activity, Takhzyro can help prevent pain and swelling attacks in people with HAE.
How do I take Takhzyro?
Takhzyro is typically started at 300 mg injected under the skin every 2 or 4 weeks.
Is it safe for me to take Takhzyro?
Takhzyro is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Takhzyro Common Side Effects
Common side effects of Takhzyro:
- Injection site reactions
- Upper respiratory infection
- Headache
- Rash
- Dizziness
- Muscle pain
- Diarrhea
Takhzyro Serious Side Effects
Serious side effects are rare with Takhzyro. Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: hives, chest tightness, difficulty breathing, wheezing, fast heartbeat, swelling of the tongue or throat
Effects of other drugs, drug classes and over-the-counter products on Takhzyro
No drug-drug interaction studies have been conducted with Takhzyro. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Takhzyro?
Takeda Pharmaceuticals
Is Takhzyro safe in pregnancy?
It is not known if Takhzyro can harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
