Key facts about Sonidegib
What dosages is Sonidegib available in?
Sonidegib is a targeted cancer medication used to treat basal cell carcinoma (BCC) that has recurred following surgery or radiation therapy, or those who are not candidates for surgery or radiation therapy.
What is Sonidegib used for?
Sonidegib is available as a 200 mg oral capsule.
How does Sonidegib work?
Sonidegib is a Hedgehog pathway inhibitor. It treats skin cancer by turning this pathway off so that the cancer cells can’t grow or spread as well.
How do I take Sonidegib?
The typical dose of Sonidegib is 200 mg orally once daily taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
Is it safe for me to take Sonidegib?
Sonidegib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Sonidegib Common Side Effects
Common side effects of Sonidegib:
- High serum creatinine levels
- Higher creatinine kinase
- Muscle spasms
- Hair loss
- High blood sugar levels
- Taste changes
- High digestive enzyme levels
- Tiredness
- Nausea
- Muscle pain
- Lower blood cell counts
- Weight loss
- Lower appetite
Sonidegib Serious Side Effects
Serious side effects are rare with Sonidegib. Contact your healthcare provider immediately if you experience any of the following:
- Serious muscle problems: painful muscle spasms, aching joints, or higher CPK levels
Effects of other drugs, drug classes and over-the-counter products on Sonidegib
The following medications may interact with Sonidegib:
- Strong and moderate CYP3A inhibitors
Who makes Sonidegib?
Various FDA-approved generic manufacturers
Is Sonidegib safe in pregnancy?
Sonidegib can cause severe birth defects or death when administered to a pregnant woman. Females who can become pregnant should use effective contraception during treatment and for at least 20 months after the last dose. Males, even those with prior vasectomy, should use condoms, to avoid potential drug exposure in both pregnant partners and female partners who can become pregnantl during treatment and for at least 8 months after the last dose. Notify your doctor immediately if you or your partner become pregnant.
