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Odomzo is the brand name for sonidegib and is available as an oral capsule.

Odomzo is a targeted cancer medication used to treat basal cell carcinoma (BCC) that has recurred following surgery or radiation therapy, or those who are not candidates for surgery or radiation therapy.

Odomzo is available as a 200 mg oral capsule.

Odomzo is a Hedgehog pathway inhibitor. It treats skin cancer by turning this pathway off so that the cancer cells can’t grow or spread as well.

The typical dose of Odomzo is 200 mg orally once daily taken on an empty stomach, at least 1 hour before or 2 hours after a meal.

Odomzo is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Odomzo:

• High serum creatinine levels
• Higher creatinine kinase
• Muscle spasms
• Hair loss
• High blood sugar levels
• Taste changes
• High digestive enzyme levels
• Tiredness
• Nausea
• Muscle pain
• Lower blood cell counts
• Weight loss
• Lower appetite

Serious side effects are rare with Odomzo. Contact your healthcare provider immediately if you experience any of the following:

• Serious muscle problems: painful muscle spasms, aching joints, or higher CPK levels

The following medications may interact with Odomzo:

• Strong and moderate CYP3A inhibitors

Novartis Pharmaceuticals

Odomzo can cause severe birth defects or death when administered to a pregnant woman. Females who can become pregnant should use effective contraception during treatment and for at least 20 months after the last dose. Males, even those with prior vasectomy, should use condoms, to avoid potential drug exposure in both pregnant partners and female partners who can become pregnantl during treatment and for at least 8 months after the last dose. Notify your doctor immediately if you or your partner become pregnant.

• Sonidegib