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Updated on 26 Apr 2024

SOLIQUA Uses, Side Effects, Interactions, Warnings & Dosing

What is SOLIQUA?

What is SOLIQUA?

SOLIQUA is the brand name for insulin glargine and lixisenatide subcutaneous injection.

What dosages is SOLIQUA available in?

What dosages is SOLIQUA available in?

SOLIQUA is available as 100 units of insulin glargine per mL and 33 mcg of lixisenatide per mL in a 3 mL single-patient use pen.

What is SOLIQUA used for?

What is SOLIQUA used for?

SOLIQUA is an insulin/GLP-1 agonist used to treat type 2 diabetes.

How does SOLIQUA work?

How does SOLIQUA work?

SOLIQUA is a combination of two medications that work together to lower blood sugar.

  • Insulin glargine (a long-acting insulin) is a hormone that directly lowers sugar in the blood
  • Lixisenatide is a glucagon-like peptide-1 (GLP-1) agonist. It tells your body to release more insulin, stops the body from releasing more sugar, and slows down digestion
How do I take SOLIQUA?

How do I take SOLIQUA?

The typical starting dose is 15 units (equivalent to 15 units of insulin glargine with 5 mcg of lixisenatide) injected under the skin once a day, within an hour before the first meal of the day. The dose will be adjusted based on your blood sugar readings, up to a maximum dose of 60 units a day (equivalent to 60 units of insulin glargine with 20 mcg of lixisenatide).

Is it safe for me to take SOLIQUA?

Is it safe for me to take SOLIQUA?

SOLIQUA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have symptoms of low blood sugar.

SOLIQUA Common Side Effects

SOLIQUA Common Side Effects

Common side effects of SOLIQUA:

  • Nausea
  • Low blood sugar
  • Common cold-like symptoms
  • Diarrhea
  • Headache
SOLIQUA Serious Side Effects

SOLIQUA Serious Side Effects

Serious side effects are rare with SOLIQUA. Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reaction
Effects of other drugs, drug classes and over-the-counter products on SOLIQUA

Effects of other drugs, drug classes and over-the-counter products on SOLIQUA

  • The following medications may interact with SOLIQUA:
  • Drugs that affect glucose metabolism: Adjustment of SOLIQUA dosage may be needed; closely monitor blood glucose
  • Antiadrenergic Drugs (e.g., beta-blockers, clonidine, guanethidine, and reserpine): Hypoglycemia signs and symptoms may be reduced
  • Effects of delayed gastric emptying on oral medications: Lixisenatide delays gastric emptying which may impact absorption of concomitantly administered oral medications. Oral contraceptives and other medications such as antibiotics and acetaminophen should be taken at least 1 hour prior to SOLIQUA administration or 11 hours after
Who makes SOLIQUA?

Who makes SOLIQUA?

sanofi-aventis U.S.

Is SOLIQUA safe in pregnancy?

Is SOLIQUA safe in pregnancy?

It is not known if SOLIQUA will harm your unborn baby. Tell
your healthcare provider if you are pregnant or plan to become pregnant while using SOLIQUA.


What to do if you missed your SOLIQUA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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