Key facts about Sofpironium
What dosages is Sofpironium available in?
Sofpironium is available as a 12.45% topical gel.
What is Sofpironium used for?
Sofpironium is an anticholinergic indicated for the treatment of underarm hyperhidrosis (excessive sweating) in adults and pediatric patients 9 years of age and older.
How does Sofpironium work?
Sofpironium is an anticholinergic that works by blocking acetylcholine receptors found on the sweat glands located in the armpit. Acetylcholine stimulates sweat production, so by blocking it, Sofpironium prevents the stimulation of these receptors and reduce sweating.
How do I take Sofpironium?
One pump of Sofpironium is applied to each underarm once a day at bedtime.
Is it safe for me to take Sofpironium?
Sofpironium is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have medical conditions that can be worsened by the anticholinergic effect of Sofpironium, including glaucoma, paralytic ileus, unstable cardiovascular status in acute hemorrhage, severe ulcerative colitis, toxic megacolon complicating ulcerative colitis, myasthenia gravis, and Sjögren ‘s syndrome.
Sofpironium Common Side Effects
Common side effects of Sofpironium: Dry mouth, Blurred vision, Application site pain, redness, irritation, rash, and itching Dilated pupils Urinary retention
Sofpironium Serious Side Effects
Serious side effects are rare with Sofpironium. Contact your healthcare provider immediately if you experience any of the following: Serious urinary retention Problems with controlling body temperature: not sweating in hot or very warm environments
Effects of other drugs, drug classes and over-the-counter products on Sofpironium
The following medications may interact with Sofpironium: Other anticholinergic medications: Avoid using together Strong CYP2D6 inhibitors: Avoid using together
Who makes Sofpironium?
Various FDA-approved generic manufacturers
Is Sofpironium safe in pregnancy?
It is not known whether Sofpironium will harm your unborn baby. Talk with your healthcare provider about the risks of taking this medication if you are pregnant or plan on becoming pregnant.













