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MEDICAL INFORMATION
Sofdra Key Facts
What is Sofdra?
Sofdra (sofpironium) is a topical gel used to treat excessive sweating.
What dosages is Sofdra available in?
Sofdra is available as a 12.45% topical gel.
What is Sofdra used for?
Sofdra is an anticholinergic indicated for the treatment of underarm hyperhidrosis (excessive sweating) in adults and pediatric patients 9 years of age and older.
How does Sofdra work?
Sofdra is an anticholinergic that works by blocking acetylcholine receptors found on the sweat glands located in the armpit. Acetylcholine stimulates sweat production, so by blocking it, Sofdra prevents the stimulation of these receptors and reduce sweating.
How do I take Sofdra?
One pump of Sofdra is applied to each underarm once a day at bedtime.
Is it safe for me to take Sofdra?
Sofdra is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have medical conditions that can be worsened by the anticholinergic effect of Sofdra, including glaucoma, paralytic ileus, unstable cardiovascular status in acute hemorrhage, severe ulcerative colitis, toxic megacolon complicating ulcerative colitis, myasthenia gravis, and Sjögren ‘s syndrome.
Sofdra Common Side Effects
Common side effects of Sofdra: Dry mouth, Blurred vision, Application site pain, redness, irritation, rash, and itching Dilated pupils Urinary retention
Sofdra Serious Side Effects
Serious side effects are rare with Sofdra. Contact your healthcare provider immediately if you experience any of the following: Serious urinary retention Problems with controlling body temperature: not sweating in hot or very warm environments
Effects of other drugs, drug classes and over-the-counter products on Sofdra
The following medications may interact with Sofdra: Other anticholinergic medications: Avoid using together Strong CYP2D6 inhibitors: Avoid using together
Who makes Sofdra?
Botanix Pharmaceuticals Ltd.
Is Sofdra safe in pregnancy?
It is not known whether Sofdra will harm your unborn baby. Talk with your healthcare provider about the risks of taking this medication if you are pregnant or plan on becoming pregnant.
What is the generic name for Sofdra?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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We are a broad skilled and passionate group of clinicians with experience of operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process
DeLon Canterbury
US Board Certified Pharmacist/PGX & Deprescribing Specialist
Aseel Hamoud Bedan
Hospital Consultant
Rajive Patel
Medical Writer
Daniel Cheung
Pharmacist Independent Prescriber, Pharmacist
Jamie Winn
US Board Certified Pharmacist
Monica Khosla
Medical Writer
Stefano Mirabello
Pharmacist Independent Prescriber, Clinical Safety Officer (CSO), Pharmacist
Ketan Patel
Pharmacist Independent Prescriber, Pharmacist
Amish Patel
Pharmacist Independent Prescriber, Superintendant Pharmacist, Pharmacist
Navin Khosla
UK Responsible Person (UKRP), Pharmacist Independent Prescriber, Clinical Safety Officer (CSO), Pharmacist
Ihtesham Sabri
Medical Director