Used for Birth Control

View SKYLA savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or SKYLA Patient Assistance Program.

Programs are suitable for individuals who want to buy SKYLA without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Bayer Healthcare

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

  • Qualified

    Rx Advantage Card

    A hand holding a dark-colored prescription savings card with various ID numbers and the label "Rx Advantage." Text below states the card is not insurance and cannot be used for Medicare or Medicaid.

    Save up to 90%

  • Unavailable

    Canadian Prescription Savings

    Manufactured by
    Powered by
    Prescription Help Logo
  • Unavailable

    Drug Coupons

    A hand holds a Copay Savings Card that states eligible patients with commercial insurance may pay as little as $0 per tube for Opzelura.
  • Available

    Patient Assistance Programs

    A picture of a patient assistance application form


Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about SKYLA

What is SKYLA?

What is SKYLA?

SKYLA is the brand name for a levonorgestrel-releasing intrauterine system.

What dosages is SKYLA available in?

What dosages is SKYLA available in?

SKYLA is available as intrauterine system consisting of a T-shaped polyethylene frame with a steroid reservoir containing 13.5 mg levonorgestrel.

What is SKYLA used for?

What is SKYLA used for?

SKYLA is a progestin that is used to prevent pregnancy for up to 3 years.

How does SKYLA work?

How does SKYLA work?

SKYLA is a small device placed in the uterus that slowly releases a progestin hormone called levonorgestrel. This hormone prevents pregnancy by stopping your ovaries from releasing an egg. Levonorgestrel also makes it difficult for sperm to reach the egg and for a fertilized egg to implant in the uterus.

How do I take SKYLA?

How do I take SKYLA?

SKYLA will need to be placed inside your uterus by your provider at their office. Once placed, it can prevent pregnancy for 3 years.

Is it safe for me to take SKYLA?

Is it safe for me to take SKYLA?

SKYLA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

  • Pregnancy or suspicion of pregnancy
  • Use as emergency contraception
  • Certain abnormal uterine anatomy
  • Acute pelvic inflammatory disease (PID) or a history of PID
  • Postpartum endometritis or infected abortion in the past 3 months
  • Uterine or cervical cancer
  • Breast cancer or other progestin-sensitive cancer
  • Uterine bleeding without a known cause
  • Untreated inflammation of the cervix or vagina, or other lower genital tract infections
  • Liver disease or liver tumor
  • A previous intrauterine device (IUD) that hasn’t been removed
SKYLA Common Side Effects

SKYLA Common Side Effects

Common side effects of SKYLA:

  • Vaginal inflammation or irritation
  • Acne
  • Stomach pain
  • Ovarian cyst
  • Headache
  • Menstrual cramps
  • Heavier menstrual bleeding
  • Breast pain or discomfort
  • Nausea
SKYLA Serious Side Effects

SKYLA Serious Side Effects

Serious side effects are rare with SKYLA. Contact your healthcare provider immediately if you experience any of the following.

  • Ectopic pregnancy: severe, unexplainable pelvic pain along with unusual vaginal bleeding
  • Severe infection: fever, chills, confusion, fatigue
Effects of other drugs, drug classes and over-the-counter products on SKYLA

Effects of other drugs, drug classes and over-the-counter products on SKYLA

  • No drug-drug interaction studies have been conducted with SKYLA. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes SKYLA?

Who makes SKYLA?

Bayer Healthcare

Is SKYLA safe in pregnancy?

Is SKYLA safe in pregnancy?

The use of SKYLA is contraindicated in pregnancy or with a suspected pregnancy and SKYLA may cause adverse pregnancy outcomes. If you become pregnant with SKYLA in place, the likelihood of ectopic pregnancy is increased and there is an increased risk of miscarriage, sepsis, premature labor, and premature delivery. Remove SKYLA, if possible, if pregnancy occurs. If SKYLA cannot be removed, follow the pregnancy closely.


What to do if you missed your SKYLA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
dollar sign

Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

FAQ logo

People Asked

Now Patient Data Security

Data Security

Our Commitment to You.

Find out moreNow Patient Data SecurityNow Patient Data Security

What is NowPatient

Telehealth and Online Pharmacy

NowPatient is a licensed online pharmacy and doctor service that is available around the world. Our service is FREE and packed with valuable features that can benefit your health such as medication reminders, educational blogs, medically approved symptoms checker, UK NHS online pharmacyprivate treatment plansRx Advantage cardhealth conditions information, affordable medications options, genetic testinghome test kitshealth riskspollen meterair quality monitor, weight loss plans, drug savings programs and lots more!

A laptop screen displaying a health dashboard with widgets showing health profile, notifications, personalized health tools, and favorite widgets including body mass index and weight loss tracking.


To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.

Download our app today

A collage showing a map with pharmacies, a questionnaire, medication details, and a person video chatting on a screen.

Can I trust NowPatient

Meet our medical team

We are a passionate group of clinicians and medical writers covering a broad range of specialities with experience operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process

Your Questions Answered

For your peace of mind, we can answer your questions quickly

We have a comprehensive list of FAQ’s on each feature page. Alternatively, for broader questions around our service just click the button below.
Find your answers