simvastatin
Used for High Cholesterol
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Manufactured by various FDA-approved generic manufacturers.
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simvastatin Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is simvastatin available in?
simvastatin is available as a 5 mg, 10 mg, 20 mg, 40 mg, and 80 mg oral tablet.
What is simvastatin used for?
simvastatin is a statin that is used for the following:
Prevention of heart or blood vessel problems (e.g., heart attack or stroke) in people at higher-risk for heart problems
Lower high “bad” cholesterol and triglyceride levels in certain people
How does simvastatin work?
simvastatin is a statin. The main way it works is by blocking an enzyme (protein) in your liver that makes cholesterol. As a result, simvastatin lowers your “bad” cholesterol (called low-density lipoprotein, or LDL). simvastatin can also raise your “good” cholesterol (called high-density lipoprotein, or HDL) levels and lower your triglyceride levels.
How do I take simvastatin?
simvastatin is dosed as follows:
- Adults: The typical dose ranges from 20 mg to 40 mg by mouth once daily in the evening
- Children age 10 years and older: The typical dose ranges from 10 mg to 40 mg by mouth once daily in the evening
Is it safe for me to take simvastatin?
simvastatin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if any of the following apply to you:
- Taking simvastatin with azole antifungals, macrolide antibiotics, certain antiviral medications, nefazodone, cyclosporine (Neoral, Gengraf, Sandimmune), or gemfibrozil (Lopid)
- Liver problems
simvastatin Common Side Effects
Common side effects of simvastatin:
- Cough, runny nose, and other symptoms of bronchitis
- Stomach pain
- Irregular heart beat
- Nausea, stomach pain ,and other symptoms of stomach inflammation
- Eczema (dry, itchy skin)
- Dizziness
- Muscle pain
simvastatin Serious Side Effects
Serious side effects are rare with simvastatin. Contact your healthcare provider immediately if you experience any of the following.
- Severe muscle damage (rhabdomyolysis): Dark brown urine, severe muscle weakness or pain, fever, tiredness
- Worsening liver problems or liver failure: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine
Effects of other drugs, drug classes and over-the-counter products on simvastatin
The following medications may interact with simvastatin:
- See full prescribing information for details regarding concomitant use of simvastatin with other drugs or grapefruit juice that increase the risk of myopathy and rhabdomyolysis
- Coumarin Anticoagulants: Obtain INR before simvastatin initiation and monitor INR during simvastatin dosage initiation or adjustment
- Digoxin: During simvastatin initiation, monitor digoxin levels
Who makes simvastatin?
Various FDA-approved generic manufacturers
Is simvastatin safe in pregnancy?
simvastatin may cause harm to your unborn baby. Discontinue simvastatin if you become pregnant.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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