Key facts about Simlandi
What is Simlandi?
Simlandi (adalimumab-ryvk) is subcutaneous injection that is a biosimilar medication to Humira.
What dosages is Simlandi available in?
Simlandi is available as a 40 mg/0.4 mL single-dose autoinjector.
What is Simlandi used for?
Simlandi treats autoimmune conditions, such as rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, Hidradenitis suppurativa (HS): Crohn’s disease, uveitis, ankylosing spondylitis, and ulcerative colitis.
How does Simlandi work?
Simlandi is a tumor necrosis factor (TNF) blocker that works by attaching to TNF-alpha and blocking the protein from attaching to its receptor, preventing it from attacking healthy cells and causing an inflammatory response.
How do I take Simlandi?
Simlandi is given as a subcutaneous injection every week or every other week.
Is it safe for me to take Simlandi?
Simlandi is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Simlandi Common Side Effects
Common side effects of Simlandi: Upper respiratory tract infection Sinus infection Headache Rash Injection site reaction1
Simlandi Serious Side Effects
Serious side effects are rare with Simlandi. Contact your healthcare provider immediately if you experience any of the following: Serious infection: fever, cough, weight loss, muscle aches, dark urine, chills, vomiting Low blood cell counts: fever that doesn’t go away, easy bruising or bleeding, pale skin Severe allergic reaction: rash, trouble breathing, swelling of your face, eyes, lips, or mouth, hives Heart failure: shortness of breath, swelling in the legs, ankles, or feet, irregular heartbeat, tiredness, sudden weight gain Liver problems: feeling tired, vomiting, yellow skin or whites of the eyes, stomach pain
Effects of other drugs, drug classes and over-the-counter products on Simlandi
The following medications may interact with Simlandi: Abatacept: Increased risk of serious infection. Anakinra: Increased risk of serious infection. Live vaccines: Avoid use with Simlandi.
Who makes Simlandi?
Alvotech and Teva Pharmaceuticals
Is Simlandi safe in pregnancy?
It is not known whether Simlandi will harm your unborn baby. Talk with your healthcare provider about the risks of taking this medication if you are pregnant or plan on becoming pregnant.
