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Adalimumab-RYVK is available as a 40 mg/0.4 mL single-dose autoinjector.

Adalimumab-RYVK treats autoimmune conditions, such as rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, Hidradenitis suppurativa (HS): Crohn’s disease, uveitis, ankylosing spondylitis, and ulcerative colitis.

Adalimumab-RYVK is a tumor necrosis factor (TNF) blocker that works by attaching to TNF-alpha and blocking the protein from attaching to its receptor, preventing it from attacking healthy cells and causing an inflammatory response.

Adalimumab-RYVK is given as a subcutaneous injection every week or every other week.

Adalimumab-RYVK is a safe and effective treatment when used for FDA approved indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Adalimumab-RYVK: Upper respiratory tract infection Sinus infection Headache Rash Injection site reaction1

Serious side effects are rare with Adalimumab-RYVK. Contact your healthcare provider immediately if you experience any of the following: Serious infection: fever, cough, weight loss, muscle aches, dark urine, chills, vomiting Low blood cell counts: fever that doesn’t go away, easy bruising or bleeding, pale skin Severe allergic reaction: rash, trouble breathing, swelling of your face, eyes, lips, or mouth, hives Heart failure: shortness of breath, swelling in the legs, ankles, or feet, irregular heartbeat, tiredness, sudden weight gain Liver problems: feeling tired, vomiting, yellow skin or whites of the eyes, stomach pain

The following medications may interact with Adalimumab-RYVK: Abatacept: Increased risk of serious infection. Anakinra: Increased risk of serious infection. Live vaccines: Avoid use with Adalimumab-RYVK.

Various FDA-approved generic manufacturers

It is not known whether Adalimumab-RYVK will harm your unborn baby. Talk with your healthcare provider about the risks of taking this medication if you are pregnant or plan on becoming pregnant.

• Simlandi