Used for Cancer

Are you tired of high medication costs? Our service offers unbeatable savings on your RUXIENCE prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by Pfizer

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

RUXIENCE cost saving options available to you

  • Qualified

    Rx Advantage Card

    NowPatient's Rx Advantage card is a simple & convenient way to save money on your RUXIENCE

    You can save up to 90%

  • Unavailable

    Canadian Prescription Savings

    Manufactured by
    Powered by
    Buy your RUXIENCE without insurance from Canada at discounts of up to 90% using NowPatient's Canadian Prescription savings program.
  • Available

    Drug Coupons

    Obtain your RUXIENCE for as little as $0 per fill. Suitable for insured individuals only.

    You can pay as little as $0

  • Available

    Patient Assistance Programs

    Obtain your RUXIENCE at no cost. Suitable for insured, underinsured and uninsured individuals

    You can receive for FREE


How it works

How to Lower Your Drug Costs

  • swoosh
    View programs

    View the savings programs that are available

  • swoosh
    Select program

    Pick the program that is suitable for you

  • swoosh

    If required, complete the online qualification check

  • swoosh
    Start Saving

    Enroll & Start Saving



Why Choose Our Service?

  • black dot icon

    Comprehensive Coverage

    Our service covers a wide range of medications, ensuring you can find savings on almost any prescription.

  • emoji icon

    Easy to Use

    Our website is user-friendly, allowing you to quickly find and apply discounts.

  • check icon

    Trusted by Many

    Thousands of users trust us to help them save on their medication costs every day.


Start Saving Today!

Lower the cost of your RUXIENCE prescription

Join the many satisfied customers who have already benefited from our prescription discount service.

Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

RUXIENCE Uses, Side Effects, Interactions, Warnings & Dosing



RUXIENCE is the brand name for rituximab-pvvr and is available as an IV infusion.

What dosages is RUXIENCE available in?

What dosages is RUXIENCE available in?

RUXIENCE is available as a 100 mg/10 mL (10 mg/mL) and 500 mg/50 mL (10 mg/mL) solution for an IV infusion.

What is RUXIENCE used for?

What is RUXIENCE used for?

RUXIENCE is a monoclonal antibody that is used for the following:

Blood cancers

  • Certain types of CD20-positive non-Hodgkin’s lymphoma (NHL) in adults and children ages 6 months and older
  • CD20-positive chronic lymphocytic leukemia (CLL) in adults

Autoimmune conditions

  • Moderate to severe rheumatoid arthritis (RA) in adults
    Granulomatosis with polyangitis (GPA) and microscopic polyangitis (MPA) in adults and children ages 2 years and older
  • Moderate to severe pemphigus vulgaris in adults
How does RUXIENCE work?

How does RUXIENCE work?

RUXIENCE is a monoclonal antibody. It targets specific immune cells called B cells that can be involved in a range of different health conditions. For example, B cells sometimes turn into cancer cells. Other times, they become overly active and cause autoimmune conditions.

How do I take RUXIENCE?

How do I take RUXIENCE?

RUXIENCE is dosed as follows: Your provider will determine your dose of RUXIENCE based on your body surface area (BSA) in m². This medication is typically given by a healthcare provider in a hospital or infusion clinic setting. Your provider might also give you other anticancer medications along with RUXIENCE.

Non-Hodgkin’s lymphoma

  • Adults: The typical dose is 375 mg/m² given as an intravenous infusion. How often you’ll receive a dose usually ranges from weekly to every 8 weeks, depending on the type of NHL you have and where you are in the treatment process.

Children: Talk with your child’s provider.

  • Chronic Lymphocytic Leukemia (CLL)
  • Adults: The typical dose is to receive one 375 mg/m² intravenous infusion before the start of chemotherapy. Then, your provider will raise your dose to 500 mg/m² infused on Day 1 of a 28-day chemotherapy cycle, for 2 to 6 cycles.

Autoimmune conditions

  • Your provider might also give you other medications along with RUXIENCE to treat your condition.


  • Adults: The typical starting dose is 1,000 mg infused IV for 2 doses, given 2 weeks apart. The typical maintenance dose is 1,000 mg infused once every 4 to 6 months, depending on your condition.


  • Adults: Your provider will determine your dose of RUXIENCE based on your body surface area (BSA) in m². The typical starting dose is 375 mg/m² given as an intravenous infusion weekly for 4 weeks. The typical maintenance dose is 250 mg/m², usually infused once every 6 months.

Children: Ask your child’s provider.

  • PV
  • Adults: The typical starting dose is 1,000 mg infused IV for 2 doses, given 2 weeks apart. The typical maintenance dose is 500 mg infused a year after the starting dose, then once every 6 months.
Is it safe for me to take RUXIENCE?

Is it safe for me to take RUXIENCE?

RUXIENCE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

RUXIENCE Common Side Effects

RUXIENCE Common Side Effects

Common side effects of RUXIENCE:

  • Fever
  • Lower white blood cell counts
  • Chills
  • Infection
  • Weakness
  • Nausea
  • Headache
  • Night sweats
  • Rash
RUXIENCE Serious Side Effects

RUXIENCE Serious Side Effects

Serious side effects are rare with RUXIENCE. Contact your healthcare provider immediately if you experience any of the following.

  • Infusion-related reaction: swelling, trouble breathing, chest pain, low blood pressure, red skin
  • Serious skin reaction: painful blisters, skin wounds, peeling skin, fever, sore throat, body aches
  • Tears in the gut: sudden and severe stomach pain, fever, chills, and nausea or vomiting that won’t go away
  • Infection: fever, chills, cough, muscle aches, very fast heartbeat, severe tiredness
  • Tumor lysis syndrome: seizures, hallucinations, nausea, tiredness, no appetite, dark-colored urine, muscle
  • cramps, numbness
    Serious heart problems: tiredness, weakness, dizziness, feeling faint, trouble breathing, pressure on the chest, pounding heart, irregular heart beat, sweating, feeling anxious, nausea
Effects of other drugs, drug classes and over-the-counter products on RUXIENCE

Effects of other drugs, drug classes and over-the-counter products on RUXIENCE

The following medications may interact with RUXIENCE:

  • Renal toxicity when used in combination with cisplatin
Who makes RUXIENCE?

Who makes RUXIENCE?


Is RUXIENCE safe in pregnancy?

Is RUXIENCE safe in pregnancy?

Talk to your healthcare provider about the risks to your unborn baby if you receive RUXIENCE during pregnancy.
Females who are able to become pregnant:

  • Your healthcare provider should do a pregnancy test to see if you are pregnant before starting RUXIENCE
  • You should use effective birth control (contraception) during treatment with RUXIENCE and for 12 months after your last dose of RUXIENCE. Talk to your healthcare provider about effective birth control
  • Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with RUXIENCE

What to do if you missed your RUXIENCE dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
dollar sign

Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

FAQ logo

Things to know

Now Patient Data Security

Data Security

Our Commitment to You.

Find out moreNow Patient Data SecurityNow Patient Data Security

What is NowPatient

Online Pharmacy & Telehealth

NowPatient is an online pharmacy & telehealth service that is available in the US and UK. Our service is FREE and packed with useful features that can help you save money on the cost of your medications, access virtual treatments, and provide tools that can help improve your overall health.  Get started today and benefit from medication reminders, private treatment plans, NHS online pharmacy, GP appointment booking, Rx savings card, Drug Coupons, US drug savings programs, health conditions information, Drug Information, genetic testing, home test kits, BMI Risks, Type 2 Diabetes Riskspollen meter, air quality monitor, and lots more!

A laptop screen displays a dashboard with various health metrics and notifications. Widgets include drug coupons, home health testing, genetic risk, diabetes risk, BMI, pollen meter, and air quality.


To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.

Download our app today

A collage showing a map with pharmacies, a questionnaire, medication details, and a person video chatting on a screen.

Can I trust NowPatient

Meet our medical team

We are a passionate group of clinicians and medical writers covering a broad range of specialities with experience operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process

Your Questions Answered

For your peace of mind, we can answer your questions quickly

We have a comprehensive list of FAQ’s on each feature page. Alternatively, for broader questions around our service just click the button below.
Find your answers