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Manufactured by various FDA-approved generic manufacturers.

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

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risdiplam Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is risdiplam available in?

What dosages is risdiplam available in?

risdiplam is available as 60 mg of risdiplam as a powder for constitution to provide 0.75 mg/mL solution.

What is risdiplam used for?

What is risdiplam used for?

risdiplam is an RNA splicing modifier that is used to treat spinal muscular atrophy (SMA) in adults and children.

How does risdiplam work?

How does risdiplam work?

risdiplam is a survival of motor neuron 2 (SMN2)-directed RNA splicing modifier. It helps your body make more SMN protein that works properly. This is thought to help improve motor skills in people with SMA.

How do I take risdiplam?

How do I take risdiplam?

The dose is based on your age and body weight. Take risdiplam after a meal at the same time every day.

  • Younger than 2 months of age: The typical dose is 0.15 mg/kg by mouth once daily
  • Age 2 months to under 2 years: The typical dose is 0.2 mg/kg by mouth once daily
  • Age 2 years and older who weigh less than 20 kg (44 lbs): The typical dose is 0.25 mg/kg by mouth once daily
  • Age 2 years and older who weigh 20 kg (44 lbs) or more: The typical dose is 5 mg by mouth once daily
Is it safe for me to take risdiplam?

Is it safe for me to take risdiplam?

risdiplam is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

risdiplam Common Side Effects

risdiplam Common Side Effects

Common side effects of risdiplam:

  • Fever
  • Diarrhea
  • Rash
risdiplam Serious Side Effects

risdiplam Serious Side Effects

Serious side effects are rare with risdiplam.

Effects of other drugs, drug classes and over-the-counter products on risdiplam

Effects of other drugs, drug classes and over-the-counter products on risdiplam

The following medications may interact with risdiplam:

  • Avoid coadministration with drugs that are substrates of multidrug and toxin extrusion (MATE) transporters
Who makes risdiplam?

Who makes risdiplam?

Various FDA-approved generic manufacturers

Is risdiplam safe in pregnancy?

Is risdiplam safe in pregnancy?

risdiplam may harm your unborn baby.
If you are a woman who can become pregnant:
Before you start your treatment with risdiplam, your healthcare provider may test you for pregnancy. Because risdiplam may harm your unborn baby, you and your healthcare provider will decide if taking risdiplam is right for you during this time. Talk to your healthcare provider about birth control methods that may be right for you. Use birth control while on treatment and for at least 1 month after stopping risdiplam. Pregnancy Registry. There is a pregnancy registry for women who take risdiplam during pregnancy. The purpose of this registry is to collect information about the health of the pregnant woman and her baby. If you are pregnant or become pregnant while receiving risdiplam, tell your healthcare provider right away. Talk to your healthcare provider about registering with the risdiplam Pregnancy Registry. Your healthcare provider can enroll you in this registry or you can enroll by calling 1-833-760-1098 or visiting risdiplam pregnancy registry


What to do if you missed your risdiplam dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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