Key facts about Evrysdi
What is Evrysdi?
Evrysdi is the brand name for risdiplam oral solution.
What dosages is Evrysdi available in?
Evrysdi is available as 60 mg of risdiplam as a powder for constitution to provide 0.75 mg/mL solution.
What is Evrysdi used for?
Evrysdi is an RNA splicing modifier that is used to treat spinal muscular atrophy (SMA) in adults and children.
How does Evrysdi work?
Evrysdi is a survival of motor neuron 2 (SMN2)-directed RNA splicing modifier. It helps your body make more SMN protein that works properly. This is thought to help improve motor skills in people with SMA.
How do I take Evrysdi?
The dose is based on your age and body weight. Take Evrysdi after a meal at the same time every day.
- Younger than 2 months of age: The typical dose is 0.15 mg/kg by mouth once daily
- Age 2 months to under 2 years: The typical dose is 0.2 mg/kg by mouth once daily
- Age 2 years and older who weigh less than 20 kg (44 lbs): The typical dose is 0.25 mg/kg by mouth once daily
- Age 2 years and older who weigh 20 kg (44 lbs) or more: The typical dose is 5 mg by mouth once daily
Is it safe for me to take Evrysdi?
Evrysdi is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Evrysdi Common Side Effects
Common side effects of Evrysdi:
- Fever
- Diarrhea
- Rash
Evrysdi Serious Side Effects
Serious side effects are rare with Evrysdi.
Effects of other drugs, drug classes and over-the-counter products on Evrysdi
The following medications may interact with Evrysdi:
- Avoid coadministration with drugs that are substrates of multidrug and toxin extrusion (MATE) transporters
Who makes Evrysdi?
Genentech, Inc.
Is Evrysdi safe in pregnancy?
Evrysdi may harm your unborn baby.
If you are a woman who can become pregnant:
Before you start your treatment with Evrysdi, your healthcare provider may test you for pregnancy. Because Evrysdi may harm your unborn baby, you and your healthcare provider will decide if taking Evrysdi is right for you during this time. Talk to your healthcare provider about birth control methods that may be right for you. Use birth control while on treatment and for at least 1 month after stopping Evrysdi. Pregnancy Registry. There is a pregnancy registry for women who take Evrysdi during pregnancy. The purpose of this registry is to collect information about the health of the pregnant woman and her baby. If you are pregnant or become pregnant while receiving Evrysdi, tell your healthcare provider right away. Talk to your healthcare provider about registering with the Evrysdi Pregnancy Registry. Your healthcare provider can enroll you in this registry or you can enroll by calling 1-833-760-1098 or visiting Evrysdi pregnancy registry
