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MEDICAL INFORMATION
Risankizumab-RZAA Key Facts
What dosages is Risankizumab-RZAA available in?
Risankizumab-RZAA is available as follows:
- Subcutaneous injection
- 150 mg/mL in each single-dose prefilled pen
- 90 mg/mL in each single-dose prefilled syringe
- 150 mg/mL in each single-dose prefilled syringe
- 180 mg/1.2 mL (150 mg/mL) in each single-dose prefilled cartridge
- 360 mg/2.4 mL (150 mg/mL) in each single-dose prefilled cartridge
- Intravenous infusion 600 mg/10 mL (60 mg/mL) in each single-dose vial
What is Risankizumab-RZAA used for?
- Risankizumab-RZAA is a monoclonal antibody that is used to treat:
- Moderate-to-severe plaque psoriasis
- Psoriatic arthritis
- Moderate-to-severe Crohn’s disease
How does Risankizumab-RZAA work?
Risankizumab-RZAA is a monoclonal antibody that works as an interleukin antagonist. It attaches to certain proteins in your immune system called interleukin-23 (IL-23) that play a role in causing inflammation. This stops the proteins from getting turned on, which helps lower inflammation.
How do I take Risankizumab-RZAA?
- Risankizumab-RZAA is dosed as follows:
- Plaque psoriasis and psoriatic arthritis: The typical starting dose is 150 mg injected under the skin once every month for the first 2 doses. Then, it’s given once every 3 months.
- Crohn’s disease: The typical starting dose is 600 mg infused through the veins (intravenous or IV) once every month for the first 3 doses. Then one month later, the dose changes to 180 mg or 360 mg injected under the skin that’s given once every 2 months.
Is it safe for me to take Risankizumab-RZAA?
Risankizumab-RZAA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Risankizumab-RZAA is contraindicated in patients with a history of serious
hypersensitivity reaction to Risankizumab-RZAA or any of the excipients.
Risankizumab-RZAA Common Side Effects
- Common side effects of Risankizumab-RZAA:
- Upper respiratory infections
- Joint pain
- Headache
- Tiredness
- Injection site reaction (e.g., bruising, redness, pain, swelling, itching, warmth, bleeding, irritation)
Risankizumab-RZAA Serious Side Effects
Serious side effects are rare with Risankizumab-RZAA. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reactions: difficulty breathing; hives; swelling of your face, lips, tongue, or throat
Infection: fever; cough; difficulty breathing; diarrhea; weakness; sweating; chills; scaly, itchy, or burning skin
Effects of other drugs, drug classes and over-the-counter products on Risankizumab-RZAA
- There are no major drug interactions listed for Risankizumab-RZAA. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes Risankizumab-RZAA?
Various FDA-approved generic manufacturers
Is Risankizumab-RZAA safe in pregnancy?
Although there are no data on Risankizumab-RZAA, monoclonal antibodies can be actively transported across the placenta, and Risankizumab-RZAA may cause immunosuppression in the in utero-exposed infant. Risankizumab-RZAA should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There is a pregnancy exposure registry that monitors outcomes in women who become pregnant while treated with Risankizumab-RZAA. Patients should be encouraged to enroll by calling 1-877-302-2161 or
visiting glow pregnancy registry
What is the brand name for Risankizumab-RZAA?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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