Used for Psoriasis

Are you tired of high medication costs? Our service offers unbeatable savings on your SKYRIZI prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by AbbVie Inc.

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

SKYRIZI cost saving options available to you

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    Rx Advantage Card

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    You can save up to 90%

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    Drug Coupons

    Obtain your SKYRIZI for as little as $0 per fill. Suitable for insured individuals only.

    You can pay as little as $0

  • Available

    Patient Assistance Programs

    Obtain your SKYRIZI at no cost. Suitable for insured, underinsured and uninsured individuals

    You can receive for FREE


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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

SKYRIZI Uses, Side Effects, Interactions, Warnings & Dosing

What is SKYRIZI?

What is SKYRIZI?

SKYRIZI is the brand name for risankizumab-rzaa and is available as an injection for subctuaneous or IV use.

What dosages is SKYRIZI available in?

What dosages is SKYRIZI available in?

SKYRIZI is available as follows:

  • Subcutaneous injection
  • 150 mg/mL in each single-dose prefilled pen
  • 90 mg/mL in each single-dose prefilled syringe
  • 150 mg/mL in each single-dose prefilled syringe
  • 180 mg/1.2 mL (150 mg/mL) in each single-dose prefilled cartridge
  • 360 mg/2.4 mL (150 mg/mL) in each single-dose prefilled cartridge
  • Intravenous infusion 600 mg/10 mL (60 mg/mL) in each single-dose vial
What is SKYRIZI used for?

What is SKYRIZI used for?

  • SKYRIZI is a monoclonal antibody that is used to treat:
  • Moderate-to-severe plaque psoriasis
  • Psoriatic arthritis
  • Moderate-to-severe Crohn’s disease
How does SKYRIZI work?

How does SKYRIZI work?

SKYRIZI is a monoclonal antibody that works as an interleukin antagonist. It attaches to certain proteins in your immune system called interleukin-23 (IL-23) that play a role in causing inflammation. This stops the proteins from getting turned on, which helps lower inflammation.

How do I take SKYRIZI?

How do I take SKYRIZI?

  • SKYRIZI is dosed as follows:
  • Plaque psoriasis and psoriatic arthritis: The typical starting dose is 150 mg injected under the skin once every month for the first 2 doses. Then, it’s given once every 3 months.
  • Crohn’s disease: The typical starting dose is 600 mg infused through the veins (intravenous or IV) once every month for the first 3 doses. Then one month later, the dose changes to 180 mg or 360 mg injected under the skin that’s given once every 2 months.
Is it safe for me to take SKYRIZI?

Is it safe for me to take SKYRIZI?

SKYRIZI is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. SKYRIZI is contraindicated in patients with a history of serious
hypersensitivity reaction to risankizumab-rzaa or any of the excipients.

SKYRIZI Common Side Effects

SKYRIZI Common Side Effects

  • Common side effects of SKYRIZI:
  • Upper respiratory infections
  • Joint pain
  • Headache
  • Tiredness
  • Injection site reaction (e.g., bruising, redness, pain, swelling, itching, warmth, bleeding, irritation)
SKYRIZI Serious Side Effects

SKYRIZI Serious Side Effects

Serious side effects are rare with SKYRIZI. Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reactions: difficulty breathing; hives; swelling of your face, lips, tongue, or throat
    Infection: fever; cough; difficulty breathing; diarrhea; weakness; sweating; chills; scaly, itchy, or burning skin
Effects of other drugs, drug classes and over-the-counter products on SKYRIZI

Effects of other drugs, drug classes and over-the-counter products on SKYRIZI

  • There are no major drug interactions listed for SKYRIZI. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes SKYRIZI?

Who makes SKYRIZI?

AbbVie Inc.

Is SKYRIZI safe in pregnancy?

Is SKYRIZI safe in pregnancy?

Although there are no data on risankizumab-rzaa, monoclonal antibodies can be actively transported across the placenta, and SKYRIZI may cause immunosuppression in the in utero-exposed infant. SKYRIZI should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There is a pregnancy exposure registry that monitors outcomes in women who become pregnant while treated with SKYRIZI. Patients should be encouraged to enroll by calling 1-877-302-2161 or
visiting  glow pregnancy registry 


What to do if you missed your SKYRIZI dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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