rifapentine
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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rifapentine Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is rifapentine available in?
rifapentine is available as a150 mg oral tablet.
What is rifapentine used for?
rifapentine is an antibiotic used to treat:
- Active tuberculosis (TB) infection
- Latent TB (you have TB bacteria in your body but you don’t have symptoms)
How does rifapentine work?
rifapentine is a rifamycin antibiotic. It blocks an enzyme the bacteria need to eventually make proteins, so the bacteria can’t grow and spread.
How do I take rifapentine?
rifapentine is dosed as follows:
- Active TB (adults and children 12 years and older)
- Initial phase: The starting dose is 600 mg twice a week for two months. Separate doses by at least 72 hours (3 full days)
- Continuation phase: 600 mg once a week for the next 4 months
- For active TB, rifapentine must be taken in combination with other anti-TB antibiotics
- Latent TB (adults and children 2 years and older)
- The dose is based on your weight, and should be taken once a week for 12 weeks. The maximum dose is 900 mg
- For latent TB, rifapentine must be taken in combination with isoniazid
Is it safe for me to take rifapentine?
rifapentine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to any rifamycin.
rifapentine Common Side Effects
Common side effects of rifapentine:
- Hepatitis, liver problems
- Headache
- Skin reaction
- Low blood cell counts
- Eye inflammation
- Stomach upset
rifapentine Serious Side Effects
Serious side effects are rare with rifapentine. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions
- C. difficile diarrhea
Effects of other drugs, drug classes and over-the-counter products on rifapentine
The following medications may interact with rifapentine:
- Protease Inhibitors and Reverse Transcriptase Inhibitors.
- Hormonal Contraceptives: Use another means of birth control
- May increase metabolism and decrease the activity of drugs metabolized by cytochrome P450 3A4 and 2C8/9. Dosage adjustments may be necessary if given concomitantly
Who makes rifapentine?
Various FDA-approved generic manufacturers
Is rifapentine safe in pregnancy?
It is not known if rifapentine will harm your unborn baby. Tell your healthcare provider if you become pregnant while taking rifapentine.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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