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MEDICAL INFORMATION
Priftin Key Facts
What is Priftin?
Priftin is the brand name for rifapentine oral tablets.
What dosages is Priftin available in?
Priftin is available as a150 mg oral tablet.
What is Priftin used for?
Priftin is an antibiotic used to treat:
- Active tuberculosis (TB) infection
- Latent TB (you have TB bacteria in your body but you don’t have symptoms)
How does Priftin work?
Priftin is a rifamycin antibiotic. It blocks an enzyme the bacteria need to eventually make proteins, so the bacteria can’t grow and spread.
How do I take Priftin?
Priftin is dosed as follows:
- Active TB (adults and children 12 years and older)
- Initial phase: The starting dose is 600 mg twice a week for two months. Separate doses by at least 72 hours (3 full days)
- Continuation phase: 600 mg once a week for the next 4 months
- For active TB, Priftin must be taken in combination with other anti-TB antibiotics
- Latent TB (adults and children 2 years and older)
- The dose is based on your weight, and should be taken once a week for 12 weeks. The maximum dose is 900 mg
- For latent TB, Priftin must be taken in combination with isoniazid
Is it safe for me to take Priftin?
Priftin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to any rifamycin.
Priftin Common Side Effects
Common side effects of Priftin:
- Hepatitis, liver problems
- Headache
- Skin reaction
- Low blood cell counts
- Eye inflammation
- Stomach upset
Priftin Serious Side Effects
Serious side effects are rare with Priftin. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions
- C. difficile diarrhea
Effects of other drugs, drug classes and over-the-counter products on Priftin
The following medications may interact with Priftin:
- Protease Inhibitors and Reverse Transcriptase Inhibitors.
- Hormonal Contraceptives: Use another means of birth control
- May increase metabolism and decrease the activity of drugs metabolized by cytochrome P450 3A4 and 2C8/9. Dosage adjustments may be necessary if given concomitantly
Who makes Priftin?
sanofi-aventis U.S.
Is Priftin safe in pregnancy?
It is not known if Priftin will harm your unborn baby. Tell your healthcare provider if you become pregnant while taking Priftin.
What is the generic name for Priftin?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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We are a broad skilled and passionate group of clinicians with experience of operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process
Rajive Patel
Medical Writer
Monica Khosla
Medical Writer
Jamie Winn
US Board Certified Pharmacist
Aseel Hamoud Bedan
Hospital Consultant
Ketan Patel
Pharmacist Independent Prescriber, Pharmacist
DeLon Canterbury
US Board Certified Pharmacist/PGX & Deprescribing Specialist
Stefano Mirabello
Pharmacist Independent Prescriber, Clinical Safety Officer (CSO), Pharmacist
Amish Patel
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Ihtesham Sabri
Medical Director
Daniel Cheung
Pharmacist Independent Prescriber, Pharmacist
Navin Khosla
UK Responsible Person (UKRP), Pharmacist Independent Prescriber, Clinical Safety Officer (CSO), Pharmacist